A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents. (Q34391586)

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21 December 2019

title

A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents (English)

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21 December 2019

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5

1 reference

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21 December 2019

10

Michael H Gelb

1 reference

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21 December 2019

1

Frederick Buckner

1 reference

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21 December 2019

2

Kohei Yokoyama

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21 December 2019

8

Wesley Van Voorhis

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21 December 2019

3

Jeffrey Lockman

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21 December 2019

7

Said Sebti

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21 December 2019

author name string

Kendra Aikenhead

series ordinal

4

1 reference

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21 December 2019

Martin Sadilek

series ordinal

6

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21 December 2019

Andrew Hamilton

series ordinal

9

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21 December 2019

language of work or name

English

0 references

publication date

1 December 2003

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

21 December 2019

number of pages

5

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based on heuristic

inferred from page(s)

published in

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21 December 2019

volume

100

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21 December 2019

issue

25

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21 December 2019

page(s)

15149-15153

1 reference

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Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase

21 December 2019

cites work

1 reference

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Farnesyl transferase inhibitors as anticancer agents

6 July 2018

1 reference

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Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major

6 July 2018

1 reference

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Current status of clinical trials of farnesyltransferase inhibitors.

6 July 2018

1 reference

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Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

6 July 2018

1 reference

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Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

6 July 2018

1 reference

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Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei

6 July 2018

1 reference

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Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine

6 July 2018

1 reference

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Antiproliferative effects and mechanism of action of SCH 56592 against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.

6 July 2018

1 reference

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The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans

6 July 2018

1 reference

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Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

6 July 2018

1 reference

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Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway.

6 July 2018

1 reference

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The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro

6 July 2018

1 reference

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Fl-160. A surface antigen of Trypanosoma cruzi that mimics mammalian nervous tissue

6 July 2018

1 reference

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The farnesyl group of H-Ras facilitates the activation of a soluble upstream activator of mitogen-activated protein kinase.

6 July 2018

1 reference

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In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas disease

21 January 2018

1 reference

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Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kda subunits as a new target for antiparasite therapeutics

21 January 2018

1 reference

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In vitro and in vivo effects of itraconazole against Trypanosoma cruzi

9 December 2018

1 reference

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Synergism in vitro of lovastatin and miconazole as anti-leishmanial agents

9 December 2018

1 reference

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Modification of the sterol composition of Trypanosoma (Schizotrypanum) cruzi epimastigotes by delta 24(25)-sterol methyl transferase inhibitors and their combinations with ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2535442100

21 January 2018

Identifiers

DOI

10.1073/PNAS.2535442100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657358%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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release_mxr6dlyrfjhijefdr2pzxlppoe

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24 November 2022

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21 December 2019

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