Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus (Q34399134)

1 August 2017

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus (English)

1 reference

C6 transcription factor hasA

1 August 2017

Aspergillus fumigatus

1 reference

inferred from

reverse claim

1 reference

GeneDB

nonribosomal peptide synthase (NRPS)

6 February 2019

1 reference

GeneDB

FAD-binding domain protein

6 February 2019

1 reference

GeneDB

bZIP transcription factor HapX

6 February 2019

1 reference

6 February 2019

1 reference

hexadehydroastechrome

1 reference

inferred from

reverse claim

1-Hydroxy-5-methoxy-3-methyl-6-[[7-(3-methyl-1,3-butadienyl)-1H-indole-3-yl]methyl]pyrazine-2(1H)-one

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Beatrix E Lechner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Suman B. Pakala

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Frank C Schroeder

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

11

Hubertus Haas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Joshua A Baccile

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Thomas A Velk

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Wen-Bing Yin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jin Woo Bok

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Liliana Losada

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

William C Nierman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Nancy P Keller

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

24 October 2014

1 reference

PubMed ID

25386169

full work available at URL

1 August 2017

https://www.frontiersin.org/articles/10.3389/fmicb.2014.00530/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.3389/fmicb.2014.00530?email=unpaywall_01@example.com

published in

Frontiers in Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.3389/fmicb.2014.00530?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

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6 July 2018

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The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis

6 July 2018

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The Sfp-type 4'-phosphopantetheinyl transferase Ppt1 of Fusarium fujikuroi controls development, secondary metabolism and pathogenicity

6 July 2018

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6 July 2018

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Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae

6 July 2018

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

6 July 2018

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Iron - A Key Nexus in the Virulence of Aspergillus fumigatus

6 July 2018

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Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus

6 July 2018

1 reference

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SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus

6 July 2018

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SRE1 regulates iron-dependent and -independent pathways in the fungal pathogen Histoplasma capsulatum

6 July 2018

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Biosynthesis and function of gliotoxin in Aspergillus fumigatus

6 July 2018

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The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation.

6 July 2018

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Iron homeostasis--Achilles' heel of Aspergillus fumigatus?

6 July 2018

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Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis

6 July 2018

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The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus

6 July 2018

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HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus

6 July 2018

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6 July 2018

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6 July 2018

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Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

6 July 2018

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Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Ferricrocin, a siderophore involved in intra- and transcellular iron distribution in Aspergillus fumigatus.

6 July 2018

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TopHat: discovering splice junctions with RNA-Seq

6 July 2018

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Iron in innate immunity: starve the invaders

6 July 2018

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Iron-based redox switches in biology

6 July 2018

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H3K9 methylation regulates growth and development in Aspergillus fumigatus

6 July 2018

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SreA-mediated iron regulation in Aspergillus fumigatus

6 July 2018

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Genes differentially expressed in conidia and hyphae of Aspergillus fumigatus upon exposure to human neutrophils

6 July 2018

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

6 July 2018

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Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization

6 July 2018

1 reference

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Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection

6 July 2018

1 reference

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Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron

6 July 2018

1 reference

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Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi

6 July 2018

1 reference

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Natural products of filamentous fungi: enzymes, genes, and their regulation

6 July 2018

1 reference

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GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence

6 July 2018

1 reference

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TM4 microarray software suite

6 July 2018

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A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production

6 July 2018

1 reference

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The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase

6 July 2018

1 reference

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The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus

6 July 2018

1 reference

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Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1.

6 July 2018

1 reference

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The Aspergillus fumigatus siderophore biosynthetic gene sidA, encoding L-ornithine N5-oxygenase, is required for virulence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Aspergillus fumigatus: saprophyte or pathogen?

6 July 2018

1 reference

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An overview of the CCAAT-box binding factor in filamentous fungi: assembly, nuclear translocation, and transcriptional enhancement.

6 July 2018

1 reference

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The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis

6 July 2018

1 reference

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Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence

6 July 2018

1 reference

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The FunCat, a functional annotation scheme for systematic classification of proteins from whole genomes

6 July 2018

1 reference

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Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores

6 July 2018

1 reference

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veA is required for toxin and sclerotial production in Aspergillus parasiticus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

LaeA, a regulator of secondary metabolism in Aspergillus spp

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage

6 July 2018

1 reference

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PKSP-dependent reduction of phagolysosome fusion and intracellular kill of Aspergillus fumigatus conidia by human monocyte-derived macrophages.

6 July 2018

1 reference

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Regulation of freA, acoA, lysF, and cycA expression by iron availability in Aspergillus nidulans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Iron and immunity: a double-edged sword.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

The role of iron in protozoan and fungal infectious diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Isolation and characterization of a new gene, sre, which encodes a GATA-type regulatory protein that controls iron transport in Neurospora crassa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

The distal GATA sequences of the sid1 promoter of Ustilago maydis mediate iron repression of siderophore production and interact directly with Urbs1, a GATA family transcription factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Role of iron in regulation of virulence genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

urbs1, a gene regulating siderophore biosynthesis in Ustilago maydis, encodes a protein similar to the erythroid transcription factor GATA-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208449

Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus.

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The siderophore system is essential for viability of Aspergillus nidulans: functional analysis of two genes encoding l-ornithine N 5-monooxygenase (sidA) and a non-ribosomal peptide synthetase (sidC).

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The siderophore biosynthetic gene SID1, but not the ferroxidase gene FET3, is required for full Fusarium graminearum virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The Aspergillus nidulans GATA factor SREA is involved in regulation of siderophore biosynthesis and control of iron uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The velvet complex governs mycotoxin production and virulence of Fusarium oxysporum on plant and mammalian hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

NPS6, encoding a nonribosomal peptide synthetase involved in siderophore-mediated iron metabolism, is a conserved virulence determinant of plant pathogenic ascomycetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

Ferrichrome in Schizosaccharomyces pombe--an iron transport and iron storage compound

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

FtmOx1, a non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

Isogenic auxotrophic mutant strains in the Aspergillus fumigatus genome reference strain AF293.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The interplay between iron and zinc metabolism in Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

Metabolomics ofAspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00530

The genetics of Aspergillus nidulans

21 January 2018

1 reference

12 December 2020

GliP, a multimodular nonribosomal peptide synthetase in Aspergillus fumigatus, makes the diketopiperazine scaffold of gliotoxin

1 reference

12 December 2020

The Aspergillus nidulans penicillin-biosynthesis gene aat (penDE) is controlled by a CCAAT-containing DNA element

1 reference

12 December 2020

Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy

1 reference

12 December 2020

Reconstitution of a secondary metabolite biosynthetic pathway in a heterologous fungal host

1 reference

12 December 2020

Fusion PCR and gene targeting in Aspergillus nidulans

1 reference

12 December 2020

FtmPT2, an N-prenyltransferase from Aspergillus fumigatus, catalyses the last step in the biosynthesis of fumitremorgin B

1 reference

12 December 2020

Iron starvation leads to increased expression of Cu/Zn-superoxide dismutase in Aspergillus

1 reference

12 December 2020

Gene expression profiling of hypoxic response in different models of senescent endothelial cells

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.3389/FMICB.2014.00530

Metabolic products of Aspergillus terreus. VII. Astechrome: An iron-containing metabolite of the strain IFO 6123.

2 references

12 April 2024

https://opencitations.net/index/api/v1/references/10.3389/FMICB.2014.00530

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.29.1510

Identifiers

DOI

10.3389/FMICB.2014.00530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25386169%20AND%20SRC:MED&resulttype=core&format=json