E2A-HLF usurps control of evolutionarily conserved survival pathways (Q34405477)

2 August 2017

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title

E2A-HLF usurps control of evolutionarily conserved survival pathways (English)

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2 August 2017

Seidel MG

1

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2 August 2017

Look AT

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 September 2001

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2 August 2017

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2 August 2017

volume

20

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2 August 2017

issue

40

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2 August 2017

page(s)

5718-5725

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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

2 August 2017

cites work

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

21 January 2018

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Id proteins control growth induction in mammalian cells

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The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

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Role for homodimerization in growth deregulation by E2a fusion proteins

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Enhanced binding of HLF/DBP heterodimers represents one mechanism of PAR protein transactivation of the factor VIII and factor IX genes

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Loss of heterozygosity in human ovarian cancer on chromosome 19q.

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Cycling vrille expression is required for a functional Drosophila clock

21 January 2018

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The Drosophila developmental gene snail encodes a protein with nucleic acid binding fingers

21 January 2018

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

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Identification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases

21 January 2018

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Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

21 January 2018

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Transcriptional repression by a novel member of the bZIP family of transcription factors

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Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

21 January 2018

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Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation

21 January 2018

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TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins

21 January 2018

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Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas

21 January 2018

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Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia

21 January 2018

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Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein

21 January 2018

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The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death

21 January 2018

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Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors

21 January 2018

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Snail/slug family of repressors: slowly going into the fast lane of development and cancer

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Human Slug is a repressor that localizes to sites of active transcription

21 January 2018

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Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif

21 January 2018

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Sequence of the cDNA encoding ITF-1, a positive-acting transcription factor

21 January 2018

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Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice

21 January 2018

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DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF

21 January 2018

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Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

21 January 2018

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Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

21 January 2018

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Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

21 January 2018

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Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

21 January 2018

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The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF

21 January 2018

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Cell transformation mediated by homodimeric E2A-HLF transcription factors

21 January 2018

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SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

21 January 2018

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A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

21 January 2018

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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

21 January 2018

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Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes

21 January 2018

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

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Oncogenic transcription factors in the human acute leukemias

21 January 2018

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The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior

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The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

21 January 2018

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Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

21 January 2018

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Genetics of programmed cell death in C. elegans: past, present and future.

21 January 2018

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Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

21 January 2018

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DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

21 January 2018

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Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

21 January 2018

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B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

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Dynamic behavior of the cadherin-based cell-cell adhesion system during Drosophila gastrulation.

21 January 2018

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Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Localization of E2A mRNA expression in developing and adult rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

B-cell-specific DNA binding by an E47 homodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Functional analysis of the murine T-cell receptor beta enhancer and characteristics of its DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Role of DBP in the circadian oscillatory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

The helix-loop-helix gene E2A is required for B cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

Asymmetric redundancy in CD4 silencer function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

E2A-HLF chimeric transcription factors in pro-B cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

Molecular genetic evidence for subtypes of oligoastrocytomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood acute lymphoblastic leukemias containing distinct E2A translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

Constitutive expression of the Id1 gene impairs mouse B cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

The role of the transcriptional activator protein DBP in circadian liver gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204591

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204591

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Dimensions Publication ID

2 August 2017

1007856505

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1 reference