Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel (Q34405882)

2 August 2017

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel (English)

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2 August 2017

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7

Peter A Calabresi

1 reference

2 August 2017

Tongguang Wang

1

1 reference

2 August 2017

Myoung-Hwa Lee

2

1 reference

2 August 2017

Elliot Choi

3

1 reference

2 August 2017

Carlos A Pardo-Villamizar

4

1 reference

2 August 2017

Sung Bin Lee

5

1 reference

2 August 2017

In Hong Yang

6

1 reference

2 August 2017

Avindra Nath

8

1 reference

2 August 2017

language of work or name

English

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publication date

29 August 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

8

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2 August 2017

e43950

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Creative Commons CC0 License

2 August 2017

start time

29 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3430617/fullTextXML

inferred from PubMed Central ID database lookup

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Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis

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Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

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Doublecortin expression levels in adult brain reflect neurogenesis

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6 July 2018

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27 October 2018

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Granzyme-b mediated cell death in the spinal cord-injured rat model

27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system.

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways.

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

Microglia Kv1.3 channels contribute to their ability to kill neurons.

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons

27 October 2018

1 reference

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PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.

27 October 2018

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Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death

27 October 2018

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Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time.

27 October 2018

1 reference

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Functional significance of cell volume regulatory mechanisms.

27 October 2018

1 reference

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Presence of the voltage-gated potassium channels sensitive to charybdotoxin in inhibitory presynaptic terminals of cultured rat hippocampal neurons.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430617

Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation

27 October 2018

1 reference

12 December 2020

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor

1 reference

12 December 2020

Increased Notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts

1 reference

12 December 2020

Vulnerability of human neurons to T cell-mediated cytotoxicity

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0043950

Identifiers

DOI

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference