Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. (Q34427178)

2 August 2017

title

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. (English)

1 reference

2 August 2017

1 reference

7

Mina J Bissell

1 reference

2 August 2017

2

Derek C Radisky

1 reference

2 August 2017

5

Jimmie E Fata

1 reference

2 August 2017

Hong Liu

1

1 reference

2 August 2017

Celeste M Nelson

series ordinal

3

1 reference

2 August 2017

Hui Zhang

series ordinal

4

1 reference

2 August 2017

Richard A Roth

series ordinal

6

1 reference

2 August 2017

language of work or name

English

0 references

publication date

7 March 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

1 reference

2 August 2017

volume

103

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2 August 2017

issue

11

1 reference

2 August 2017

page(s)

4134-4139

1 reference

Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes

2 August 2017

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6 July 2018

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The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3

6 July 2018

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Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells

6 July 2018

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6 July 2018

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Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration

6 July 2018

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14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s)

6 July 2018

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Regulation of TSC2 by 14-3-3 binding

6 July 2018

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6 July 2018

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Akt regulates growth by directly phosphorylating Tsc2

6 July 2018

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

6 July 2018

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Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

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6 July 2018

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6 July 2018

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6 July 2018

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Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

6 July 2018

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6 July 2018

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6 July 2018

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AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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21 January 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/16537497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bud formation precedes the appearance of differential cell proliferation during branching morphogenesis of mouse lung epithelium in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0511342103

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference