IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells. (Q34428659)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells (English)

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9 March 2020

2

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9 March 2020

author name string

Tom L Van Belle

1

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9 March 2020

Tom Boonefaes

3

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9 March 2020

Xiao-Qing Wei

4

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9 March 2020

Georges Leclercq

5

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9 March 2020

Johan Grooten

6

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9 March 2020

language of work or name

English

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publication date

20 September 2012

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9 March 2020

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9 March 2020

volume

7

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9 March 2020

issue

9

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9 March 2020

page(s)

e45299

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Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

20 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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6 July 2018

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6 July 2018

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IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine

6 July 2018

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6 July 2018

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Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen.

6 July 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

6 July 2018

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

6 July 2018

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Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology

6 July 2018

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6 July 2018

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Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells

6 July 2018

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IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.

6 July 2018

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6 July 2018

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6 July 2018

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

6 July 2018

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IL-2 knockout recipient mice reject islet cell allografts

6 July 2018

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Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447928

IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway

27 October 2018

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IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development

27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

27 October 2018

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27 October 2018

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IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

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IL-15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12 / IL-4 stimulation in vitro.

27 October 2018

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27 October 2018

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Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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12 December 2020

High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro

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12 December 2020

IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells

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12 December 2020

Serum interleukin-15 is elevated in systemic lupus erythematosus

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12 December 2020

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

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12 December 2020

Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitis

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12 December 2020

Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens

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12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

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12 December 2020

10.1371/JOURNAL.PONE.0045299

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23028916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028916%20AND%20SRC:MED&resulttype=core&format=json