CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells (Q34709777)

4 August 2017

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells (English)

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4 August 2017

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Pushpa Pandiyan

1

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4 August 2017

Lixin Zheng

2

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4 August 2017

Satoru Ishihara

3

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4 August 2017

Jennifer Reed

4

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4 August 2017

Michael J Lenardo

5

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4 August 2017

language of work or name

English

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publication date

4 November 2007

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4 August 2017

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4 August 2017

8

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4 August 2017

1353-1362

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4 August 2017

12

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

4 August 2017

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7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

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7 January 2021

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

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7 January 2021

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

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7 January 2021

A function for interleukin 2 in Foxp3-expressing regulatory T cells

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7 January 2021

Fueling regulation: IL-2 keeps CD4+ Treg cells fit

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7 January 2021

Mechanisms of suppression by suppressor T cells

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7 January 2021

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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7 January 2021

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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7 January 2021

Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity

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7 January 2021

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

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7 January 2021

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

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7 January 2021

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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7 January 2021

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

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7 January 2021

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.

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7 January 2021

CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4

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7 January 2021

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

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7 January 2021

Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.

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7 January 2021

Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo

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7 January 2021

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

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7 January 2021

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

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7 January 2021

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

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7 January 2021

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

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7 January 2021

IL-4 modulation of CD4+CD25+ T regulatory cell-mediated suppression

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7 January 2021

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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7 January 2021

Cellular survival: a play in three Akts

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7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production.

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7 January 2021

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

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7 January 2021

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

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7 January 2021

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

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7 January 2021

Interleukin-7 is a survival factor for CD4+ CD25+ T-cells and is expressed by diabetes-suppressive dendritic cells

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7 January 2021

IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition.

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7 January 2021

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

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7 January 2021

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

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7 January 2021

Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation

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7 January 2021

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

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7 January 2021

The role of BH3-only proteins in the immune system

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7 January 2021

Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango

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7 January 2021

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

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7 January 2021

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

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7 January 2021

Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo.

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7 January 2021

IL-2 and autoimmune disease

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7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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7 January 2021

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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7 January 2021

Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes

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7 January 2021

In vivo sites and cellular mechanisms of T reg cell-mediated suppression

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7 January 2021

Identifiers

DOI

10.1038/NI1536

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4 August 2017

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