Evolutionary aspects of enzyme dynamics (Q34430849)

2 August 2017

1 reference

title

Evolutionary aspects of enzyme dynamics (English)

1 reference

2 August 2017

Judith P Klinman

1

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2 August 2017

Amnon Kohen

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

10 September 2014

1 reference

Journal of Biological Chemistry

2 August 2017

published in

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2 August 2017

volume

289

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2 August 2017

issue

44

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2 August 2017

page(s)

30205-30212

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Picosecond-resolved fluorescent probes at functionally distinct tryptophans within a thermophilic alcohol dehydrogenase: relationship of temperature-dependent changes in fluorescence to catalysis

2 August 2017

cites work

1 reference

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Protein mass-modulated effects in the catalytic mechanism of dihydrofolate reductase: beyond promoting vibrations

6 July 2018

1 reference

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Hydrogen tunneling in a prokaryotic lipoxygenase

6 July 2018

1 reference

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Extension and limits of the network of coupled motions correlated to hydride transfer in dihydrofolate reductase

6 July 2018

1 reference

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Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase.

6 July 2018

1 reference

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Preservation of protein dynamics in dihydrofolate reductase evolution

6 July 2018

1 reference

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Water networks contribute to enthalpy/entropy compensation in protein-ligand binding

6 July 2018

1 reference

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Hydrogen tunneling links protein dynamics to enzyme catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Relationship of femtosecond-picosecond dynamics to enzyme-catalyzed H-transfer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Identification of a long-range protein network that modulates active site dynamics in extremophilic alcohol dehydrogenases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Effects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Update 1 of: Tunneling and dynamics in enzymatic hydride transfer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Choreographing an enzyme's dance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Hidden alternative structures of proline isomerase essential for catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

A 21st century revisionist's view at a turning point in enzymology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

The hydrophobic effect and its role in cold denaturation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Free-energy landscape of enzyme catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Relating protein motion to catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Hydrogen tunneling and protein motion in enzyme reactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Network of coupled promoting motions in enzyme catalysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Electrostatic stabilization of a thermophilic cold shock protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Entropy-enthalpy compensation: fact or artifact?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Mechanisms and uses of hydrogen exchange

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Hydrogen tunneling in enzyme reactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Cold denaturation of proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215204

Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Fast protein motions are coupled to enzyme H-transfer reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Tetrameric NAD-dependent alcohol dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Crystallization and preliminary X-ray diffraction studies of an alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.565515

The contribution of hydrophobic bonds to the thermal stability of protein conformations

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25210031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.R114.565515

1 reference

2 August 2017

1 reference

2 August 2017

1 reference