Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission (Q34435558)

2 August 2017

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title

Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission (English)

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2 August 2017

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Zhu J

1

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2 August 2017

Lallemand-Breitenbach V

series ordinal

2

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2 August 2017

de Thé H

series ordinal

3

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2 August 2017

language of work or name

English

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publication date

1 October 2001

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2 August 2017

number of pages

9

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inferred from page(s)

published in

Oncogene

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2 August 2017

volume

20

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2 August 2017

issue

49

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2 August 2017

page(s)

7257-7265

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Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

2 August 2017

cites work

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RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

21 January 2018

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A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest.

21 January 2018

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All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells

21 January 2018

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A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.

21 January 2018

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

21 January 2018

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A viral activator of gene expression functions via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo

21 January 2018

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Positive and negative regulation of granulopoiesis by endogenous RARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

21 January 2018

1 reference

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Coordinate regulation of RARgamma2, TBP, and TAFII135 by targeted proteolysis during retinoic acid-induced differentiation of F9 embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

A sustained increase in the endogenous level of cAMP reduces the retinoid concentration required for APL cell maturation to near physiological levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

PML induces a novel caspase-independent death process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Chromosomal translocations in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Transcriptional regulation: Kamikaze activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Role of PML in cell growth and the retinoic acid pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Arsenic trioxide induces apoptosis of HPV16 DNA-immortalized human cervical epithelial cells and selectively inhibits viral gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Immunosuppressive effects of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

Arsenic trioxide (As2O3)-induced apoptosis and differentiation in retinoic acid-resistant acute promyelocytic leukemia model in hGM-CSF-producing transgenic SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

A critical role for the proteasome activator PA28 in the Hsp90-dependent protein refolding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

Retinoic acid and arsenic: towards oncogene-targeted treatments of acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204852

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204852

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Dimensions Publication ID

2 August 2017

1046166173

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