Carcinogenic risks of dioxin: mechanistic considerations (Q34438479)

2 August 2017

1 reference

title

Carcinogenic risks of dioxin: mechanistic considerations (English)

1 reference

2 August 2017

Michael Schwarz

1

1 reference

2 August 2017

Klaus E Appel

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

Regulatory Toxicology and Pharmacology

2 August 2017

published in

1 reference

2 August 2017

volume

43

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

19-34

1 reference

Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: an example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Modeling receptor-mediated processes with dioxin: implications for pharmacokinetics and risk assessment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cancer mortality in German male workers exposed to phenoxy herbicides and dioxins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cancer incidence in a population accidentally exposed to 2,3,7,8-tetrachlorodibenzo-para-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Health effects of dioxin exposure: a 20-year mortality study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes an Ah receptor-dependent and ARNT-independent increase in membrane levels and activity of p60(Src).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Single cell analysis of switch-like induction of CYP1A1 in liver cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Effects of 2,3,7,8-tetrachloro- and 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin on the proliferation of preneoplastic liver cells in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Effects of polychlorinated biphenyls in rat liver: correlation between primary subcellular effects and promoting activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Active cell death: role in hepatocarcinogenesis and subtypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Hepatic Foci in Rats after Diethylnitrosamine Initiation and 2,3,7,8-Tetrachlorodibenzo-p-dioxin Promotion: Evaluation of a Quantitative Two-Cell Model and of CYP 1A1/1A2 as a Dosimeter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Meta-analysis of dioxin cancer dose response for three occupational cohorts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Nonadditive hepatic tumor promoting effects by a mixture of two structurally different polychlorinated biphenyls in female rat livers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Regulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of the DNA binding activity of transcriptional factors via nuclear protein phosphorylation in guinea pig adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo- p-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Estimation of the cumulated exposure to polychlorinated dibenzo-p-dioxins/furans and standardized mortality ratio analysis of cancer mortality by dose in an occupationally exposed cohort

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Early indicators of response in biologically based risk assessment for nongenotoxic carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The phenotypic stability of altered hepatic foci: effect of the short-term withdrawal of phenobarbital and of the long-term feeding of purified diets after the withdrawal of phenobarbital.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Animal models of human response to dioxins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The PAS superfamily: sensors of environmental and developmental signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Liver tumour promoting activity of 3,4,5,3',4'-pentachlorobiphenyl and its interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The phenotypic stability of altered hepatic foci: effects of withdrawal and subsequent readministration of phenobarbital.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Global assessment of organic contaminants in farmed salmon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Carcinogenicity of TCDD: experimental, mechanistic, and epidemiologic evidence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits DNA synthesis in rat primary hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins: an expanded and updated international cohort study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

A mechanistic model of effects of dioxin on gene expression in the rat liver.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Functional analysis of the human cytochrome P4501A1 (CYP1A1) gene enhancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The Ah receptor and the mechanism of dioxin toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

TCDD-mediated alterations in the AhR-dependent pathway in Seveso, Italy, 20 years after the accident

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Threshold phenomena and long-distance activation of transcription by RNA polymerase II

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Two EGF molecules contribute additively to stabilization of the EGFR dimer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Receptor mechanisms and dose-response models for the effects of dioxins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on initiation and promotion of GST-P-positive foci in rat liver: A quantitative analysis of experimental data using a stochastic model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Effects of polychlorinated biphenyls in rat liver: quantitative analysis of enzyme-altered foci

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

On the significance of the role of cellular stress response reactions in the toxic actions of dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

WY-14,643-mediated promotion of hepatocarcinogenesis in connexin32-wild-type and connexin32-null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cell proliferation and carcinogenesis models: general principles with illustrations from the rodent liver system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Quantitative analysis of enzyme-altered liver foci in rats initiated with diethylnitrosamine and promoted with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments--I. Single agent regimen.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. 4. Effects of multiple-dose treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on peripheral lymphocyte subpopulations of a non-human primate (Callithrix jacchus)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Molecular biology of the aromatic hydrocarbon (dioxin) receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Cause specific mortality and cancer incidence among employees exposed to 2,3,7,8-TCDD after a 1953 reactor accident

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The role of receptors in multistage carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Stage of tumor progression, progressor agents, and human risk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The multistage nature of chemically induced hepatocarcinogenesis in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered hepatic foci.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Mechanistic aspects--the dioxin (aryl hydrocarbon) receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Tumour promotion by TCDD in skin of HRS/J hairless mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Modeling the number and size of hepatic focal lesions following exposure to 2,3,7,8-TCDD.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Lipoxin A4: a new class of ligand for the Ah receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Potency of mixtures of polychlorinated biphenyls as inducers of dioxin receptor-regulated CYP1A activity in rat hepatocytes and H4IIE cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Promotion of preneoplastic foci in rat liver with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 1,2,3,4,6,7,8-heptachloro-dibenzo-p-dioxin and a defined mixture of 49 polychlorinated dibenzo-p-dioxins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins: comparison between defined mixtures and their constituents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Tumor promotion in the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Apoptosis and multistage carcinogenesis in rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Role of receptors in human and rodent hepatocarcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Receptor-mediated events and the evaluation of the Environmental Protection Agency (EPA) of dioxin risks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Significant shortcomings of the U.S. Environmental Protection Agency's latest draft risk characterization for dioxin-like compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Risk assessment for 2,3,7,8-p-dioxin (TCDD) based on an epidemiologic study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Dioxin revisited: developments since the 1997 IARC classification of dioxin as a human carcinogen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Inhibition of apoptosis during 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Quantitative analysis of dose- and time-dependent promotion of four phenotypes of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Induction of altered hepatic foci by a mixture of dioxin-like compounds with and without 2,2',4,4',5,5'-hexachlorobiphenyl in female Sprague-Dawley rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Contribution of Planar (0–1 Ortho) and Nonplanar (2–4 Ortho) Fractions of Aroclor 1260 to the Induction of Altered Hepatic Foci in Female Sprague–Dawley Rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Regulation of prostaglandin endoperoxide H synthase-2 induction by dioxin in rat hepatocytes: possible c-Src-mediated pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Induction and localization of cytochrome P450 1B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Differences in kinetics of induction and reversibility of TCDD-induced changes in cell proliferation and CYP1A1 expression in female Sprague-Dawley rat liver.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Hepatocarcinogenesis in Female Sprague-Dawley Rats following Discontinuous Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds"

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Serum dioxin concentrations and breast cancer risk in the Seveso Women's Health Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Genetic and molecular aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Consultation on assessment of the health risk of dioxins; re-evaluation of the tolerable daily intake (TDI): Executive Summary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin and 17beta-estradiol in male Sprague-Dawley rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

Real-time measurements of kinetics of EGF binding to soluble EGF receptor monomers and dimers support the dimerization model for receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced activation of a protein tyrosine kinase, pp60src, in murine hepatic cytosol using a cell-free system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

inferred from DOI database lookup

7 January 2021

based on heuristic

Aryl hydrocarbon or dioxin receptor: biologic and toxic responses.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

inferred from DOI database lookup

7 January 2021

based on heuristic

The AH-receptor: genetics, structure and function

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2005.05.008

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YRTPH.2005.05.008

1 reference

2 August 2017

1 reference