Spatial and temporal diversity in genomic instability processes defines lung cancer evolution (Q34442770)

2 August 2017

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution (English)

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Richard Mitter

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Stuart Horswell

Stuart Horswell

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Nicholas McGranahan

Nicholas McGranahan

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Ignacio Varela

Ignacio Varela

15

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David C. Wedge

David C Wedge

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Peter Van Loo

Peter Van Loo

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Siow-Ming Lee

Siow-Ming Lee

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Robert C. Rintoul

Robert C Rintoul

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Charles Swanton

Charles Swanton

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Sharmin Begum

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Sharmin Begum

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2 August 2017

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Thierry Voet

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David Jones

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Andrew J Rowan

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Benjamin Phillimore

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Max Salm

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Peter Campbell

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Sam M Janes

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Gordon Stamp

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Mariam Jamal-Hanjani

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Seema Shafi

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Tanya Ahmad

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Mary Falzon

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Aengus Stewart

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Elza C de Bruin

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Nirupa Murugaesu

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2 August 2017

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Bradley Spencer-Dene

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2 August 2017

Lucy Yates

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2 August 2017

Eva Grönroos

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2 August 2017

Madiha A Muhammad

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2 August 2017

John Marshall

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2 August 2017

Doris M Rassl

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2 August 2017

Martin Forster

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2 August 2017

David Lawrence

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2 August 2017

Arrigo Capitanio

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2 August 2017

Timothy T Harkins

29

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2 August 2017

Clarence C Lee

30

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2 August 2017

Warren Tom

31

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2 August 2017

Enock Teefe

32

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2 August 2017

Shann-Ching Chen

33

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2 August 2017

Adam Rabinowitz

35

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2 August 2017

Nik Matthews

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2 August 2017

language of work or name

English

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publication date

1 October 2014

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2 August 2017

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346

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251-256

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6206

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Discovery and saturation analysis of cancer genes across 21 tumour types

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Pan-cancer patterns of somatic copy number alteration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

The causes and consequences of genetic heterogeneity in cancer evolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Management of non-small-cell lung cancer: recent developments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Signatures of mutational processes in human cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Evidence for APOBEC3B mutagenesis in multiple human cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

End-joining, translocations and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Punctuated evolution of prostate cancer genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

6 July 2018

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Genomic landscape of non-small cell lung cancer in smokers and never-smokers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

The life history of 21 breast cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Absolute quantification of somatic DNA alterations in human cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Chromosomal instability confers intrinsic multidrug resistance.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Allele-specific copy number analysis of tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Diverse somatic mutation patterns and pathway alterations in human cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

The mutation spectrum revealed by paired genome sequences from a lung cancer patient

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

A small-cell lung cancer genome with complex signatures of tobacco exposure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Somatic mutations affect key pathways in lung adenocarcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Characterizing the cancer genome in lung adenocarcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Epidermal growth factor receptor mutations in lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

On the origin of G --> T transversions in lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Mutations of the BRAF gene in human cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636050

Fast and accurate short read alignment with Burrows-Wheeler transform

6 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

The Sequence Alignment/Map format and SAMtools

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Sequence-specific error profile of Illumina sequencers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Estimating the Dimension of a Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Comprehensive genomic characterization of squamous cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

TIGRA: a targeted iterative graph routing assembler for breakpoint assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Diverse mechanisms of somatic structural variations in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

Circos: an information aesthetic for comparative genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

The landscape of cancer genes and mutational processes in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

TumorBoost: normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

CalMaTe: a method and software to improve allele-specific copy number of SNP arrays for downstream segmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1253462

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1253462

1 reference

2 August 2017

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1 reference

2 August 2017

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