Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing (Q36256943)

13 August 2017

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing (English)

1 reference

13 August 2017

1

1 reference

13 August 2017

Pierre Martinez

11

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Stuart Horswell

Stuart Horswell

2

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Nicholas McGranahan

Nicholas McGranahan

8

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Ignacio Varela

Ignacio Varela

6

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Paul A. Bates

Paul A Bates

17

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Charles Swanton

Charles Swanton

25

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Sharmin Begum

13

Sharmin Begum

1 reference

13 August 2017

23

P Andrew Futreal

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13 August 2017

12

Benjamin Phillimore

1 reference

13 August 2017

4

Andrew J Rowan

1 reference

13 August 2017

5

Max P Salm

1 reference

13 August 2017

19

Lisa Pickering

1 reference

13 August 2017

21

David L Nicol

1 reference

13 August 2017

18

Gordon Stamp

1 reference

13 August 2017

7

Rosalie Fisher

1 reference

13 August 2017

24

Aengus Stewart

1 reference

13 August 2017

9

Nicholas Matthews

1 reference

13 August 2017

15

Bradley Spencer-Dene

1 reference

13 August 2017

22

Steven Hazell

1 reference

13 August 2017

James Larkin

3

1 reference

13 August 2017

Claudio R Santos

10

1 reference

13 August 2017

Adam Rabinowitz

14

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13 August 2017

Sakshi Gulati

16

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13 August 2017

Martin Gore

20

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13 August 2017

language of work or name

English

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publication date

2 February 2014

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13 August 2017

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13 August 2017

46

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13 August 2017

225-233

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13 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/ng.2891

13 August 2017

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cites work

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Comprehensive molecular characterization of clear cell renal cell carcinoma

30 September 2017

1 reference

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Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

30 September 2017

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Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

30 September 2017

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

30 September 2017

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Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

30 September 2017

1 reference

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Deciphering signatures of mutational processes operative in human cancer

30 September 2017

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Why Your New Cancer Biomarker May Never Work: Recurrent Patterns and Remarkable Diversity in Biomarker Failures

30 September 2017

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Intratumor heterogeneity: evolution through space and time

30 September 2017

1 reference

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BAP1 loss defines a new class of renal cell carcinoma

30 September 2017

1 reference

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The life history of 21 breast cancers

30 September 2017

1 reference

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers

30 September 2017

1 reference

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

30 September 2017

1 reference

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VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

30 September 2017

1 reference

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Variation in the mutation rate across mammalian genomes

30 September 2017

1 reference

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Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality

30 September 2017

1 reference

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An integrated semiconductor device enabling non-optical genome sequencing

30 September 2017

1 reference

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Sequence-specific error profile of Illumina sequencers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Tumour evolution inferred by single-cell sequencing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Integrative genomics viewer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Mutation patterns in cancer genomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Parallel evolution of tumour subclones mimics diversity between tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Intratumor heterogeneity: seeing the wood for the trees.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Genetic variegation of clonal architecture and propagating cells in leukaemia

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Chromosome 9p deletions identify an aggressive phenotype of clear cell renal cell carcinoma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Single column discrepancy and dynamic max-mini optimizations for quickly finding the most parsimonious evolutionary trees.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636053

5 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24487277

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2891

1 reference

13 August 2017

1 reference

13 August 2017

1 reference