The role of chaperone-mediated autophagy in huntingtin degradation (Q34447527)

2 August 2017

The role of chaperone-mediated autophagy in huntingtin degradation (English)

1 reference

2 August 2017

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7

Zheng-Hong Qin

1 reference

2 August 2017

Lin Qi

1

1 reference

2 August 2017

Xing-Ding Zhang

2

1 reference

2 August 2017

Jun-Chao Wu

3

1 reference

2 August 2017

Fang Lin

4

1 reference

2 August 2017

Jin Wang

5

1 reference

2 August 2017

Marian DiFiglia

6

1 reference

2 August 2017

language of work or name

English

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publication date

11 October 2012

1 reference

2 August 2017

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2 August 2017

7

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2 August 2017

10

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2 August 2017

e46834

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Creative Commons Attribution 4.0 International

2 August 2017

start time

11 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species

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The zinc finger transcription factor ZKSCAN3 promotes prostate cancer cell migration

6 July 2018

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Does Huntingtin play a role in selective macroautophagy?

6 July 2018

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Termination of autophagy and reformation of lysosomes regulated by mTOR

6 July 2018

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Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Chaperone-mediated autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

6 July 2018

1 reference

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Mammalian macroautophagy at a glance

6 July 2018

1 reference

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Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Protein homeostasis and aging: taking care of proteins from the cradle to the grave

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Methods to monitor chaperone-mediated autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy: process and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Trinucleotide Repeat Disorders

6 July 2018

1 reference

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Autophagy and neurodegeneration: when the cleaning crew goes on strike

6 July 2018

1 reference

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The roles of intracellular protein-degradation pathways in neurodegeneration

6 July 2018

1 reference

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

The molecular machinery of autophagy: unanswered questions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy: many paths to the same end.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Huntingtin processing in pathogenesis of Huntington disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy: in sickness and in health

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Development by self-digestion: molecular mechanisms and biological functions of autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

A receptor for the selective uptake and degradation of proteins by lysosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Polypeptide import and degradation by isolated lysosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Peptide sequences that target cytosolic proteins for lysosomal proteolysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Isolation of subcellular organelles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy delivers misfolded secretory proteins accumulated in endoplasmic reticulum to vacuoles in the filamentous fungus Aspergillus oryzae.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

27 October 2018

How shall I eat thee?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy regulates the processing of amino terminal huntingtin fragments

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Nuclear factor kappaB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Lysosomes, a meeting point of proteins, chaperones, and proteases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469570

Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress

27 October 2018

1 reference

12 December 2020

A rapid and simplified method for the preparation of lysosomal membranes from rat liver

1 reference

12 December 2020

Peptide sequences that target proteins for enhanced degradation during serum withdrawal

1 reference

12 December 2020

Selective binding and uptake of ribonuclease A and glyceraldehyde-3-phosphate dehydrogenase by isolated rat liver lysosomes

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0046834

Identifiers

DOI

1 reference

release_2zjm6dwhmvhhfc66naimzhry44

2 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2zjm6dwhmvhhfc66naimzhry44

24 November 2022

mapped directly with Wikidata item

PMCID

3469570

1 reference

2 August 2017

1 reference