Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo (Q34452334)

2 August 2017

title

Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo (English)

1 reference

2 August 2017

1 reference

Amy N Hicks

1

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Baisong Lu

object named as

Baisong Lu

4

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Paul A Overbeek

object named as

Paul A Overbeek

7

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Karl-Erik Andersson

5

object named as

Karl-Erik Andersson

1 reference

2 August 2017

Diego Lorenzetti

2

1 reference

2 August 2017

Jonathan Gilley

3

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2 August 2017

Carol Miligan

6

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2 August 2017

Ronald Oppenheim

8

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2 August 2017

Colin E Bishop

9

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2 August 2017

language of work or name

English

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publication date

17 October 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

10

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2 August 2017

page(s)

e47869

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

17 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

1 reference

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NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy

6 July 2018

1 reference

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Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development

6 July 2018

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Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Wld(S), Nmnats and axon degeneration--progress in the past two decades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Overexpression of Wld(S) or Nmnat2 in mauthner cells by single-cell electroporation delays axon degeneration in live zebrafish.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Wallerian degeneration, wld(s), and nmnat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

6 July 2018

1 reference

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Synaptic dysfunction in disease and following injury in the developing and adult nervous system: caveats in the choice of therapeutic intervention

6 July 2018

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Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis

6 July 2018

1 reference

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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

6 July 2018

1 reference

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Transposons for gene therapy!

6 July 2018

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A network dysfunction perspective on neurodegenerative diseases

6 July 2018

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An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax

6 July 2018

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Identification of a novel human nicotinamide mononucleotide adenylyltransferase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Neuron death in vertebrate development: in vitro methods

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.

6 July 2018

1 reference

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Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474723

Nicotinamide-mononucleotide adenylyltransferase from Sulfolobus solfataricus

27 October 2018

1 reference

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Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system

27 October 2018

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Paralysis and growth of the musculoskeletal system in the embryonic chick

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The development of motoneurons in the embryonic spinal cord of the mouse mutant, muscular dysgenesis (mdg/mdg): survival, morphology, and biochemical differentiation

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Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon

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Evidence that Very Slow Wallerian Degeneration in C57BL/Ola Mice is an Intrinsic Property of the Peripheral Nerve

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10.1371/JOURNAL.PONE.0047869

Identifiers

DOI

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2 August 2017

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1 reference

2 August 2017

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