Inhibition of vascular endothelial growth factor in the treatment of solid tumors (Q34457421)

2 August 2017

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title

Inhibition of vascular endothelial growth factor in the treatment of solid tumors (English)

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2 August 2017

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Kim Margolin

1

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2 August 2017

publication date

1 January 2002

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2 August 2017

published in

Current Oncology Reports

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2 August 2017

volume

4

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2 August 2017

issue

1

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2 August 2017

page(s)

20-28

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Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer

2 August 2017

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Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer

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Gene therapy strategies for tumor antiangiogenesis

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Expression of platelet-derived endothelial cell growth factor and vascular endothelial growth factor in hepatocellular carcinoma and portal vein tumor thrombus

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The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors

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Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

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Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer

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Heterogeneity of angiogenic activity in a human liposarcoma: a proposed mechanism for "no take" of human tumors in mice

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Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis

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Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival

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12 December 2020

Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice

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12 December 2020

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.

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12 December 2020

Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells

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12 December 2020

Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in patients with ductal carcinoma in situ of the breast

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12 December 2020

Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor121

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12 December 2020

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

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12 December 2020

Prognostic significance of vascular endothelial growth factor protein levels in oral and oropharyngeal squamous cell carcinoma

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12 December 2020

Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression

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12 December 2020

Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer

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12 December 2020

Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors

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12 December 2020

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma

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12 December 2020

Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer

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12 December 2020

Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver

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12 December 2020

Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia

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12 December 2020

Expression of vascular endothelial growth factor in primary superficial bladder cancer

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12 December 2020

Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma

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Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro

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Angiogenic capacity and lung-colonizing potential in vivo is increased in weakly metastatic B16F1 cells and decreased in highly metastatic BL6 cells by phorbol esters

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Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data

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Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

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Role of vascular endothelial growth factor/vascular permeability factor in the pathogenesis of Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphomas

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Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor

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12 December 2020

Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein

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12 December 2020

Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated adult rats

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12 December 2020

Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480.

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12 December 2020

Vascular endothelial growth factor in squamous cell head and neck carcinoma: expression and prognostic significance

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12 December 2020

Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy

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12 December 2020

Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts

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12 December 2020

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

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12 December 2020

Clinical trials referral resource: Current clinical trials of the anti-VEGF monoclonal antibody bevacizumab

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12 December 2020

Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer

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12 December 2020

Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA.

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12 December 2020

Correlation of Vascular Endothelial Growth Factor Content With Recurrences, Survival, and First Relapse Site in Primary Node-Positive Breast Carcinoma After Adjuvant Treatment

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12 December 2020

Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasms

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12 December 2020

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

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12 December 2020

Angiogenesis and prostate cancer: in vivo and in vitro expression of angiogenesis factors by prostate cancer cells

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12 December 2020

Vascular endothelial growth factor and platelet-derived growth factor are potential angiogenic and metastatic factors in human breast cancer

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12 December 2020

Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells

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12 December 2020

Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1beta

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12 December 2020

Prognostic value of vascular endothelial growth factor expression in gastric carcinoma

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12 December 2020

Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas.

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12 December 2020

Vascular permeability factor/vascular endothelial growth factor and its receptors in oral and laryngeal squamous cell carcinoma and dysplasia

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12 December 2020

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

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12 December 2020

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract

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12 December 2020

Vascular endothelial growth factor expression predicts outcome and lymph node metastasis in squamous cell carcinoma of the esophagus

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12 December 2020

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

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12 December 2020

Expression of vascular endothelial growth factor correlates with hematogenous recurrence in gastric carcinoma

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12 December 2020

Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis

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12 December 2020

Intense vascular sprouting from rat femoral vein induced by prostaglandins E1 and E2.

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12 December 2020

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

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12 December 2020

Vascular endothelial growth factor expression in head and neck squamous cell carcinoma

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12 December 2020

Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo

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12 December 2020

Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ.

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12 December 2020

Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting

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12 December 2020

Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells.

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12 December 2020

Progestin regulation of vascular endothelial growth factor in human breast cancer cells

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12 December 2020

Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer

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12 December 2020

Importance of VEGF for breast cancer angiogenesis in vivo: implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin

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12 December 2020

Melanoma-associated expression of vascular endothelial growth factor and its receptors FLT-1 and KDR.

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12 December 2020

Expression of vascular endothelial growth factor and thrombospondin-1 in colorectal carcinoma

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12 December 2020

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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12 December 2020

Association of vascular endothelial growth factor expression with angiogenesis and lymph node metastasis in nasopharyngeal carcinoma

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12 December 2020

Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer

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12 December 2020

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

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12 December 2020

PGE2 and angiogenesis

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12 December 2020

Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis

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12 December 2020

Oncogenes, p53, and tumor angiogenesis

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12 December 2020

Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas

1 reference

12 December 2020

Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy.

1 reference

12 December 2020

'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples

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12 December 2020

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

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12 December 2020

Vascular endothelial growth factor expression as a prognostic index in serous ovarian cystoadenocarcinomas: relationship with MIB1 immunostaining

1 reference

12 December 2020

Correlation between expression of vascular endothelial growth factor and tumor vascularity, and patient outcome in human gastric carcinoma

1 reference

12 December 2020

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

12 December 2020

Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.

1 reference

12 December 2020

Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

1 reference

12 December 2020

Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

1 reference

12 December 2020

Prognostic significance of angiogenesis in human pancreatic cancer

1 reference

12 December 2020

Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor.

1 reference

12 December 2020

Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies

1 reference

12 December 2020

Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck.

1 reference

12 December 2020

Expression and regulation of vascular endothelial growth factor in osteoblasts

1 reference

12 December 2020

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

1 reference

12 December 2020

Is there a role for nitric oxide in tumor angiogenesis?

1 reference

12 December 2020

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

1 reference

12 December 2020

Angiogenic heterogeneity: regulation of neoplastic angiogenesis by the organ microenvironment

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12 December 2020

Vascular endothelial growth factor expression in early stage ovarian carcinoma.

1 reference

12 December 2020

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

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12 December 2020

Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia

1 reference

12 December 2020

Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells

1 reference

12 December 2020

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

1 reference

12 December 2020

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

1 reference

12 December 2020

Gene therapy for antiangiogenesis

1 reference

12 December 2020

Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma.

1 reference

12 December 2020

Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms

1 reference

12 December 2020

Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients

1 reference

12 December 2020

Correlation of vascular endothelial growth factor expression and microvessel density in cervical intraepithelial neoplasia

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF) and its receptors

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12 December 2020

Vascular Permeability Factor, Fibrin, and the Pathogenesis of Tumor Stroma Formationa

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12 December 2020

Tumor angiogenesis and vascular endothelial growth factor expression in stage I lung adenocarcinoma

1 reference

12 December 2020

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

1 reference

12 December 2020

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1 reference

12 December 2020

Different angiogenic pathways characterize superficial and invasive bladder cancer

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12 December 2020

Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents

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12 December 2020

Implication of vascular endothelial growth factor and p53 status for angiogenesis in noninvasive colorectal carcinoma

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12 December 2020

Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic disease

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12 December 2020

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12 December 2020

Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis

1 reference

12 December 2020

Vascular endothelial growth factor expression in non-small-cell lung cancer: prognostic significance in squamous cell carcinoma

1 reference

12 December 2020

Molecular and biological properties of the vascular endothelial growth factor family of proteins

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12 December 2020

10.1007/S11912-002-0044-9

Identifiers

DOI

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Dimensions Publication ID

2 August 2017

1012291085

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