Acyclic nucleoside phosphonates: a key class of antiviral drugs (Q34464655)

2 August 2017

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title

Acyclic nucleoside phosphonates: a key class of antiviral drugs (English)

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2 August 2017

2

Antonín Holý

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2 August 2017

1

Erik De Clercq

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publication date

1 November 2005

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Nature Reviews Drug Discovery

2 August 2017

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2 August 2017

4

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2 August 2017

928-940

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2 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrd1877

2 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Renal safety of tenofovir in HIV treatment-experienced patients.

21 January 2018

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21 January 2018

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Pancreatic toxic effects associated with co-administration of didanosine and tenofovir in HIV-infected adults

21 January 2018

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Fatal lactic acidosis and acute renal failure after addition of tenofovir to an antiretroviral regimen containing didanosine

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21 January 2018

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Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue

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6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity

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Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates

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21 January 2018

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Novel acyclic nucleoside phosphonate analogues with potent anti-hepatitis B virus activities

21 January 2018

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Antiadenovirus activities of several classes of nucleoside and nucleotide analogues

21 January 2018

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(S)-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity

21 January 2018

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Synthesis of 5′-deoxyuridine 5′-phosphonic acid

31 March 2020

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Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells

31 March 2020

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Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation

31 March 2020

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Potent differentiation-inducing properties of the antiretroviral agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in the rat choriocarcinoma (RCHO) tumor cell model

31 March 2020

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Potent antitumor activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine in choriocarcinoma-bearing rats

31 March 2020

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Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells.

31 March 2020

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Cidofovir for the treatment of Kaposi's sarcoma in an HIV-negative homosexual man

31 March 2020

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Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: report of a case

31 March 2020

1 reference

Tenofovir disoproxil fumarate

31 March 2020

1 reference

Clinical pharmacokinetics of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine in human immunodeficiency virus-infected patients.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD1877

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2 August 2017

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PubMed ID

16264436