Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers. (Q40738807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948417%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

title

Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers (English)

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9 December 2019

2

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9 December 2019

Eric Deutsch

3

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9 December 2019

William Vainchenker

8

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9 December 2019

author name string

Bassam Abdulkarim

1

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9 December 2019

Heddia Chagraoui

4

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9 December 2019

Laurence Maggiorella

5

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9 December 2019

Jerome Thierry

6

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9 December 2019

François Eschwege

7

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9 December 2019

Salem Chouaïb

9

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9 December 2019

Jean Bourhis

10

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9 December 2019

language of work or name

English

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publication date

1 April 2002

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9 December 2019

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9 December 2019

volume

21

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9 December 2019

issue

15

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9 December 2019

page(s)

2334-2346

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Antiviral approaches for cancers related to Epstein-Barr virus and human papillomavirus

9 December 2019

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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

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21 January 2018

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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

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Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis

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Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7.

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Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

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Cyclin A is a functional target of retinoblastoma tumor suppressor protein-mediated cell cycle arrest

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Potent inhibition of hemangiosarcoma development in mice by cidofovir

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Clinical uses of cidofovir

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Radiation-enhanced expression of E6/E7 transforming oncogenes of human papillomavirus-16 in human cervical carcinoma

21 January 2018

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The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines

21 January 2018

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

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7 January 2021

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7 January 2021

Intracellular Metabolism and Action of Acyclic Nucleoside Phosphonates on DNA Replication

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948417%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 December 2019

1021120144

0 references

1 reference