Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. (Q34467657)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

review article

1 reference

title

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

5 December 2019

main subject

0 references

author

J. Silvio Gutkind

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

Gutkind JS

series ordinal

1

1 reference

2 August 2017

11 July 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

Science's STKE : signal transduction knowledge environment

5 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

volume

2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

re1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

Neurobiology of the Caenorhabditis elegans genome.

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

How receptors talk to trimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The many faces of G protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G protein beta gamma subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Molecular basis for interactions of G protein betagamma subunits with effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Evolution of the mammalian G protein alpha subunit multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of phosphoinositide-specific phospholipase C isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Inositol trisphosphate and calcium signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Inositol trisphosphate, a novel second messenger in cellular signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Complexity and diversity of mammalian adenylyl cyclases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Mammalian membrane-bound adenylyl cyclases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G protein regulation of adenylate cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Transmembrane signalling pathways initiating cell growth in fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Neuroendocrine lung cancer: a receptor-mediated disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Growth factor and peptide receptors in small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Growth factors and oncogenes in human gastrointestinal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Human cytomegalovirus encodes three G protein-coupled receptor homologues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The DNA sequence of the human cytomegalovirus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Two G protein oncogenes in human endocrine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Potent transforming activity of the G13 alpha subunit defines a novel family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Early signals in the mitogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

MAP kinase pathways in yeast: for mating and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

How receptor tyrosine kinases activate Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Protein modules and signalling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The PTB domain: a new protein module implicated in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine rece

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Stimulation of mitogen-activated protein kinase by G protein-coupled alpha(2)-adrenergic receptors does not require agonist-elicited endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Lysophosphatidic acid: G-protein signalling and cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Gi-mediated tyrosine phosphorylation of Grb2 (growth-factor-receptor-bound protein 2)-bound dynamin-II by lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Stimulation of the phosphatidylinositol pathway can induce T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of transforming G protein-coupled receptors induces rapid tyrosine phosphorylation of cellular proteins, including p125FAK and the p130 v-src substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signal characteristics of G protein-transactivated EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Membrane-anchored growth factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Structure and function of phosphoinositide 3-kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

p21ras: an oncoprotein functioning in growth factor-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of Ras-mediated signalling: more than one way to skin a cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signal transduction pathways involving the Raf proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in Rat-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

In search of a function for the Ras-like GTPase Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of transcription by MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Galpha12 and Galpha13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Dependence of activated Galpha12-induced G1 to S phase cell cycle progression on both Ras/mitogen-activated protein kinase and Ras/Rac1/Jun N-terminal kinase cascades in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Association of the proto-oncogene product dbl with G protein betagamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein beta gamma subunit in human embryonal kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The Src family tyrosine kinase is involved in Rho-dependent activation of c-Jun N-terminal kinase by Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Divergent signaling pathways link focal adhesion kinase to mitogen-activated protein kinase cascades. Evidence for a role of paxillin in c-Jun NH(2)-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Gq signaling in cardiac adaptation and maladaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Tyrosine kinase and c-Jun NH2-terminal kinase mediate hypertrophic responses to prostaglandin F2alpha in cultured neonatal rat ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gbetagamma and Galphaq/11 subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of Apoptosis by α-Subunits of G12 and G13 Proteins via Apoptosis Signal-regulating Kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Primary structure of BMK1: a new mammalian map kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Signaling from G protein-coupled receptors to the c-jun promoter involves the MEF2 transcription factor. Evidence for a novel c-jun amino-terminal kinase-independent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

A mammalian scaffold complex that selectively mediates MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Protection from natural killer cell-mediated lysis by HLA-G expression on target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Calmodulin activates phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Interactions between the Gs/protein kinase A and the Ras/MAP-kinase signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Cyclic AMP-dependent activation of Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Activation of ternary complex factor Elk-1 by stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Multiple basal promoter elements determine the level of human c-fos transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

The role of protein kinase C in cell surface signal transduction and tumour promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.40.RE1

21 January 2018

Identifiers

DOI

10.1126/STKE.2000.40.RE1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752597%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference