Small molecule-triggered Cas9 protein with improved genome-editing specificity (Q34470608)

2 August 2017

title

Small molecule-triggered Cas9 protein with improved genome-editing specificity (English)

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2 August 2017

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Kevin M Davis

1

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2 August 2017

Vikram Pattanayak

2

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2 August 2017

David B Thompson

3

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2 August 2017

John A Zuris

4

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2 August 2017

David R Liu

5

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2 August 2017

language of work or name

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6 April 2015

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2 August 2017

published in

Nature Chemical Biology

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2 August 2017

volume

11

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2 August 2017

issue

5

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2 August 2017

page(s)

316-318

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A split-Cas9 architecture for inducible genome editing and transcription modulation

2 August 2017

cites work

1 reference

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

6 July 2018

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

6 July 2018

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An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells

6 July 2018

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

6 July 2018

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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

6 July 2018

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Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.

6 July 2018

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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

6 July 2018

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

6 July 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

6 July 2018

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Genetic screens in human cells using the CRISPR-Cas9 system

6 July 2018

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

6 July 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 July 2018

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

6 July 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 July 2018

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DNA targeting specificity of RNA-guided Cas9 nucleases

6 July 2018

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 July 2018

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Near-infrared fluorescent proteins for multicolor in vivo imaging

6 July 2018

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Efficient genome editing in zebrafish using a CRISPR-Cas system

6 July 2018

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RNA-guided human genome engineering via Cas9

6 July 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 July 2018

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Directed evolution of a small-molecule-triggered intein with improved splicing properties in mammalian cells

6 July 2018

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Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels

6 July 2018

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Control of transcription factor activity and osteoblast differentiation in mammalian cells using an evolved small-molecule-dependent intein

6 July 2018

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Directed evolution of ligand dependence: small-molecule-activated protein splicing

6 July 2018

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Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen

6 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1793

RNA-programmed genome editing in human cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1793

21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.1793

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Dimensions Publication ID

2 August 2017

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1 reference

2 August 2017

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