Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts (Q34474381)

2 August 2017

title

Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts (English)

1 reference

2 August 2017

Natalie R Gassman

1

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author name string

Donna F Stefanick

2

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2 August 2017

Padmini S Kedar

3

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2 August 2017

Julie K Horton

4

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2 August 2017

Samuel H Wilson

5

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2 August 2017

language of work or name

English

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publication date

7 November 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

11

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2 August 2017

page(s)

e49301

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Creative Commons CC0 License

2 August 2017

copyright license

start time

7 November 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3492265/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks

6 July 2018

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Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

6 July 2018

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Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair

6 July 2018

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Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

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Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks.

6 July 2018

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Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells

6 July 2018

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The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

6 July 2018

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Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

6 July 2018

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Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage

6 July 2018

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Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS.

6 July 2018

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Parthanatos, a messenger of death

6 July 2018

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Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

6 July 2018

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Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.

6 July 2018

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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1

6 July 2018

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6 July 2018

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A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

6 July 2018

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Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions

6 July 2018

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Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen.

6 July 2018

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6 July 2018

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

6 July 2018

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Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

6 July 2018

1 reference

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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

6 July 2018

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Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences

6 July 2018

1 reference

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Poly(ADP-ribose) polymerase: a molecular nick-sensor

6 July 2018

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Poly(ADP-ribose) in the cellular response to DNA damage

6 July 2018

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Role of poly(ADP-ribose) formation in DNA repair

6 July 2018

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Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.

6 July 2018

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Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death.

21 January 2018

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Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

21 January 2018

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Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.

21 January 2018

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Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase

21 January 2018

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Coenzymatic activity of randomly broken or intact double-stranded DNAs in auto and histone H1 trans-poly(ADP-ribosylation), catalyzed by poly(ADP-ribose) polymerase (PARP I).

21 January 2018

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Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

21 January 2018

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12 December 2020

Improved immunodetection of nuclear antigens after sodium dodecyl sulfate treatment of formaldehyde-fixed cells

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12 December 2020

A backup DNA repair pathway moves to the forefront

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12 December 2020

Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway

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12 December 2020

A new form of cell death: Parthanatos

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12 December 2020

10.1371/JOURNAL.PONE.0049301

Identifiers

DOI

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2 August 2017

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2 August 2017

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