A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1. (Q34512240)

2 August 2017

A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1. (English)

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2 August 2017

W Zhang

1

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2 August 2017

X Zeng

2

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2 August 2017

K J Briggs

3

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2 August 2017

R Beaty

4

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2 August 2017

B Simons

5

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2 August 2017

R-W Chiu Yen

6

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2 August 2017

M A Tyler

7

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2 August 2017

H-C Tsai

8

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2 August 2017

Y Ye

9

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2 August 2017

G S Gesell

10

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2 August 2017

J G Herman

11

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2 August 2017

S B Baylin

12

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2 August 2017

D N Watkins

13

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2 August 2017

language of work or name

English

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publication date

15 February 2010

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2 August 2017

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2 August 2017

29

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17

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2 August 2017

2467-2476

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https://scigraph.springernature.com/pub.10.1038/onc.2010.12

2 August 2017

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Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

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Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor

7 July 2018

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Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma

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Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin

7 July 2018

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Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival

7 July 2018

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

7 July 2018

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A conditional feedback loop regulates Ras activity through EphA2.

7 July 2018

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Eph receptor signalling casts a wide net on cell behaviour

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Ephrin-A1 expression contributes to the malignant characteristics of {alpha}-fetoprotein producing hepatocellular carcinoma

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EPHA2/EFNA1 expression in human gastric cancer.

7 July 2018

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Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

7 July 2018

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Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly

7 July 2018

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Mechanisms and functions of Eph and ephrin signalling

7 July 2018

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The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

7 July 2018

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Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells

7 July 2018

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Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

7 July 2018

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7 July 2018

The Hallmarks of Cancer

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Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B

7 July 2018

1 reference

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TRANSFAC: an integrated system for gene expression regulation

7 July 2018

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Eph receptors and ephrins: effectors of morphogenesis

7 July 2018

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The carboxy-terminal end of the candidate tumor suppressor gene HIC-1 is phylogenetically conserved

7 July 2018

1 reference

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Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer

7 July 2018

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A simplified system for generating recombinant adenoviruses

7 July 2018

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Genomic organization of the murine Miller-Dieker/lissencephaly region: conservation of linkage with the human region

7 July 2018

2 references

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7 July 2018

https://api.crossref.org/works/10.1038%2FONC.2010.12

A revision of the lissencephaly and Miller-Dieker syndrome critical regions in chromosome 17p13.3.

31 March 2020

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Lessons from hereditary colorectal cancer

7 July 2018

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p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025282

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025282

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

Up-regulation of ephrin-A1 during melanoma progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

Ephrin-A1 promotes the malignant progression of intestinal tumors in Apc(min/+) mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.12

High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20154726

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.12

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference