Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function (Q34567627)

3 August 2017

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function (English)

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3 August 2017

Jeremy J Heit

1

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3 August 2017

Asa A Apelqvist

2

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3 August 2017

Xueying Gu

3

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3 August 2017

Monte M Winslow

4

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3 August 2017

Joel R Neilson

5

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3 August 2017

Gerald R Crabtree

6

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3 August 2017

Seung K Kim

7

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3 August 2017

language of work or name

English

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publication date

1 September 2006

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3 August 2017

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3 August 2017

443

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3 August 2017

7109

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3 August 2017

345-349

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https://scigraph.springernature.com/pub.10.1038/nature05097

3 August 2017

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cites work

Intrinsic regulators of pancreatic beta-cell proliferation

1 reference

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7 January 2021

Molecular control of cell cycle progression in the pancreatic beta-cell

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Risk for posttransplant Diabetes mellitus with current immunosuppressive medications

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7 January 2021

Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

NFAT signaling: choreographing the social lives of cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Calcineurin B1 is essential for positive but not negative selection during thymocyte development

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

The calcineurin phosphatase complex modulates immunogenic B cell responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Regulation of insulin gene transcription by a Ca(2+)-responsive pathway involving calcineurin and nuclear factor of activated T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Effects of tacrolimus (FK506) on human insulin gene expression, insulin mRNA levels, and insulin secretion in HIT-T15 cells

1 reference

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7 January 2021

Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Genetic factors in type 2 diabetes: the end of the beginning?

1 reference

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7 January 2021

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes

1 reference

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7 January 2021

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

1 reference

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7 January 2021

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

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7 January 2021

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

1 reference

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7 January 2021

Calcineurin/NFAT signaling in osteoblasts regulates bone mass

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05097

7 January 2021

Identifiers

DOI

10.1038/NATURE05097

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Dimensions Publication ID

3 August 2017

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1 reference