Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters (Q34568808)

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English	Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters (English)

1 reference

Europe PubMed Central

3 August 2017

single-nucleotide polymorphism

1 reference

based on heuristic

inferred from title

author name string

Supratim Choudhuri

1

1 reference

Europe PubMed Central

3 August 2017

Curtis D Klaassen

2

1 reference

Europe PubMed Central

3 August 2017

publication date

1 July 2006

1 reference

Europe PubMed Central

3 August 2017

International Journal of Toxicology

1 reference

Europe PubMed Central

3 August 2017

25

1 reference

Europe PubMed Central

3 August 2017

4

1 reference

Europe PubMed Central

3 August 2017

231-259

1 reference

Europe PubMed Central

3 August 2017

Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Chemical control of phospholipid distribution across bilayer membranes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Mammalian ABC transporters in health and disease

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The multidrug resistance protein family.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A family of drug transporters: the multidrug resistance-associated proteins.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Genetic dissection of the function of mammalian P-glycoproteins

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The complexities of hepatic drug transport: current knowledge and emerging concepts.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10)

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Some major landmarks in the path from nuclein to human genome (1).

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Usefulness of studies on the molecular mechanism of action of herbals/botanicals: The case of St. John's wort

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Considerations in the design and development of transport inhibitors as adjuncts to drug therapy

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Complete characterization of the human ABC gene family.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ABC of oral bioavailability: transporters as gatekeepers in the gut.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Role of MRP2 and GSH in intrahepatic cycling of toxins

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Importance of P-glycoprotein at blood-tissue barriers

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The effect of rifampin treatment on intestinal expression of human MRP transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: a comparison of human BSEP with rat Bsep.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Is the multidrug transporter a flippase?

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The ATP switch model for ABC transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Structural, mechanistic and clinical aspects of MRP1.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Physiology and pathophysiology of sphingolipid metabolism and signaling

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Expression and functional characterization of human ABC transporter ABCG2 variants in insect cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Regulation of rat multidrug resistance protein 2 by classes of prototypical microsomal enzyme inducers that activate distinct transcription pathways

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of functionally variant MDR1 alleles among European Americans and African Americans

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Functional analysis of SNPs variants of BCRP/ABCG2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MRP3, an organic anion transporter able to transport anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Role of ABCG2/BCRP in biology and medicine

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The MRP family of drug efflux pumps

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transcriptional regulators of the human multidrug resistance 1 gene: recent views

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Role of the breast cancer resistance protein (ABCG2) in drug transport

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Single nucleotide polymorphisms modify the transporter activity of ABCG2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Enterohepatic transport of bile salts and genetics of cholestasis

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of two different states of P-glycoprotein in its catalytic cycle: role of the linker region in the transition between these two states

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

RETRACTED: Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Prostanoid transport by multidrug resistance protein 4 (MRP4/ABCC4) localized in tissues of the human urogenital tract

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

MRP6 (ABCC6) detection in normal human tissues and tumors.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transcriptional regulation of ABC drug transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A general pattern for substrate recognition by P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Novel mutations identified in the human multidrug resistance-associated protein 2 (MRP2/ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transp

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The human multidrug resistance protein 2 gene: functional characterization of the 5'-flanking region and expression in hepatic cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Characterization of 5'-flanking region of human MRP3

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Topotecan is a substrate for multidrug resistance associated protein 4.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Human multidrug resistance associated protein 4 confers resistance to camptothecins.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transporter-mediated Drug Interactions

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

How does P-glycoprotein recognize its substrates?

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Molecular pharmacology of renal organic anion transporters

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of a functional initiator sequence in the human MDR1 promoter.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding sta

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1080%2F10915810600746023

21 January 2018

Identifiers

10.1080/10915810600746023

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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