Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues (Q34572493)

3 August 2017

title

Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues (English)

1 reference

3 August 2017

L M McCracken

1

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3 August 2017

M L McCracken

2

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3 August 2017

D H Gong

3

1 reference

3 August 2017

J R Trudell

4

1 reference

3 August 2017

R A Harris

5

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3 August 2017

language of work or name

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1 July 2010

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ACS Chemical Neuroscience

3 August 2017

published in

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3 August 2017

volume

1

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3 August 2017

issue

7

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3 August 2017

page(s)

482

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An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors

3 August 2017

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7 July 2018

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X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

7 July 2018

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7 July 2018

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Ethanol's molecular targets

7 July 2018

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Subunit-specific potentiation of recombinant glycine receptors by NV-31, a bilobalide-derived compound

7 July 2018

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X-ray structure of a prokaryotic pentameric ligand-gated ion channel

7 July 2018

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Normal-mode analysis of the glycine alpha1 receptor by three separate methods

7 July 2018

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Conformational dynamics of the alphaM3 transmembrane helix during acetylcholine receptor channel gating

7 July 2018

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Tryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed

7 July 2018

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7 July 2018

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State-dependent cross-linking of the M2 and M3 segments: functional basis for the alignment of GABAA and acetylcholine receptor M3 segments.

7 July 2018

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Cholesterol interacts with transmembrane alpha-helices M1, M3, and M4 of the Torpedo nicotinic acetylcholine receptor: photolabeling studies using [3H]Azicholesterol

7 July 2018

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Molecular tuning of fast gating in pentameric ligand-gated ion channels

7 July 2018

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Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies

7 July 2018

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Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.

7 July 2018

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Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

7 July 2018

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

7 July 2018

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A speed limit for conformational change of an allosteric membrane protein

7 July 2018

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GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization

7 July 2018

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7 July 2018

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Structure and gating mechanism of the acetylcholine receptor pore

7 July 2018

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Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure

7 July 2018

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Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer

7 July 2018

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The glycinergic inhibitory synapse.

7 July 2018

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

7 July 2018

1 reference

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Anesthetics and ion channels: molecular models and sites of action

7 July 2018

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Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

7 July 2018

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A transmembrane site determines sensitivity of neuronal nicotinic acetylcholine receptors to general anesthetics.

7 July 2018

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Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

7 July 2018

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Nicotinic receptor fourth transmembrane domain: hydrogen bonding by conserved threonine contributes to channel gating kinetics

7 July 2018

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Functional effects of periodic tryptophan substitutions in the alpha M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor

7 July 2018

1 reference

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Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge

7 July 2018

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Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors

7 July 2018

1 reference

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Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Glycine and glycine receptor immunoreactivity in brain and spinal cord

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Cloning and expression of the 58 kd beta subunit of the inhibitory glycine receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Accessibility to residues in transmembrane segment four of the glycine receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Homology modeling of a human glycine alpha 1 receptor reveals a plausible anesthetic binding site

27 October 2018

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Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system

27 October 2018

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Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Comparative modeling of a GABAA alpha1 receptor using three crystal structures as templates

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038641

Predicting the transmembrane secondary structure of ligand-gated ion channels

27 October 2018

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Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors.

27 October 2018

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Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating

27 October 2018

1 reference

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G protein-coupled receptor activation: analysis of a highly constrained, "straitjacketed" rhodopsin

27 October 2018

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12 December 2020

Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: secondary structure implications

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12 December 2020

Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels

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Anion permeation in GABA- and glycine-gated channels of mammalian cultured hippocampal neurons

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Identifying the lipid-protein interface and transmembrane structural transitions of the Torpedo Na,K-ATPase using hydrophobic photoreactive probes

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Identifiers

DOI

10.1021/CN100019G

1 reference

3 August 2017

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3 August 2017

1 reference