Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment (Q34574516)

3 August 2017

Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment (English)

1 reference

3 August 2017

1 reference

Takanori So

1

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3 August 2017

Jianxun Song

2

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3 August 2017

Katsuji Sugie

3

1 reference

3 August 2017

Amnon Altman

4

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3 August 2017

Michael Croft

5

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3 August 2017

language of work or name

English

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publication date

24 February 2006

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

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3 August 2017

103

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3 August 2017

10

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3 August 2017

3740-3745

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IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

The costimulation-regulated duration of PKB activation controls T cell longevity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

An epigenetic view of helper T cell differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

The role of OX40 ligand interactions in the development of the Th2 response to the gastrointestinal nematode parasite Heligmosomoides polygyrus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Transcription: tantalizing times for T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

The potency of TCR signaling differentially regulates NFATc/p activity and early IL-4 transcription in naive CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Dendritic cell regulation of TH1-TH2 development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Stat6 regulation of in vivo IL-4 responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Transcription of the interleukin 4 gene is regulated by multiple promoter elements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Transcriptional regulation of th2 differentiation by inducible costimulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450148

Defective T Cell Differentiation in the Absence of Jnk1

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600205103

Conventional, naive CD4+ T cells provide an initial source of IL-4 during Th2 differentiation

21 January 2018

1 reference

12 December 2020

Stat5 activation plays a critical role in Th2 differentiation

1 reference

12 December 2020

The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells

1 reference

12 December 2020

Human naive CD4 T cells produce interleukin-4 at priming and acquire a Th2 phenotype upon repetitive stimulations in neutral conditions

1 reference

12 December 2020

CD28 costimulation promotes the production of Th2 cytokines

1 reference

12 December 2020

Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses

1 reference

12 December 2020

ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling

1 reference

12 December 2020

Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

1 reference

12 December 2020

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

12 December 2020

OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0600205103

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3 August 2017

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3 August 2017

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