Recombinant protein expression for therapeutic applications (Q34598013)

3 August 2017

1 reference

title

Recombinant protein expression for therapeutic applications (English)

1 reference

3 August 2017

Dana C Andersen

1

1 reference

3 August 2017

Lynne Krummen

series ordinal

2

1 reference

3 August 2017

publication date

1 April 2002

1 reference

Current Opinion in Biotechnology

3 August 2017

published in

1 reference

3 August 2017

volume

13

1 reference

3 August 2017

issue

2

1 reference

3 August 2017

page(s)

117-123

1 reference

Industrial choices for protein production by large-scale cell culture

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Advances in Escherichia coli production of therapeutic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Therapeutic antibody expression technology

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

IRES bicistronic expression vectors for efficient creation of stable mammalian cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Rapid establishment of high-producing cell lines using dicistronic vectors with glutamine synthetase as the selection marker

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Stabilized, long-term expression of heterodimeric proteins from tricistronic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

High-level production of recombinant proteins in CHO cells using a dicistronic DHFR intron expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Development of stable cell lines for production or regulated expression using matrix attachment regions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Streptogramin-based gene regulation systems for mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

A high-throughput alphavirus-based expression cloning system for mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Transient gene expression: recombinant protein production with suspension-adapted HEK293-EBNA cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Getting the glycosylation right: implications for the biotechnology industry

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Construction of stable BHK-21 cells coexpressing human secretory glycoproteins and human Gal(beta 1-4)GlcNAc-R alpha 2,6-sialyltransferase alpha 2,6-linked NeuAc is preferentially attached to the Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)-branch of

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Genetic engineering of α2,6-sialyltransferase in recombinant CHO cells and its effects on the sialylation of recombinant interferon-γ.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Proliferation control of mammalian cells by the tumor suppressor IRF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Enhanced productivity during controlled proliferation of BHK cells in continuously perfused bioreactors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

The effect of the dilution rate on CHO cell physiology and recombinant interferon-gamma production in glucose-limited chemostat culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Engineering Chinese hamster ovary (CHO) cells to achieve an inverse growth - associated production of a foreign protein, beta-galactosidase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Understanding and modulating apoptosis in industrial cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Metabolic control of recombinant protein N-glycan processing in NS0 and CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Phosphate feeding improves high-cell-concentration NS0 myeloma culture performance for monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

N-acetylcysteine increases the biosynthesis of recombinant EPO in apoptotic Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Serum protects protein-free competent Chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Recombinant protein expression in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

DegP-coexpression minimizes inclusion-body formation upon overproduction of recombinant penicillin acylase in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Effect of sequences of the active-site dipeptides of DsbA and DsbC on in vivo folding of multidisulfide proteins in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

The periplasmic Escherichia coli peptidylprolyl cis,trans-isomerase FkpA. I. Increased functional expression of antibody fragments with and without cis-prolines.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

ClpB and HtpG facilitate de novo protein folding in stressed Escherichia coli cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Coordinated, differential expression of two genes through directed mRNA cleavage and stabilization by secondary structures

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Translational level is a critical factor for the secretion of heterologous proteins in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Regulatable arabinose-inducible gene expression system with consistent control in all cells of a culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Characterization of an oxygen-dependent inducible promoter, the nar promoter of Escherichia coli, to utilize in metabolic engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

High-cell-density fermentation for production of L-N-carbamoylase using an expression system based on the Escherichia coli rhaBAD promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Avoiding acetate accumulation in Escherichia coli cultures using feedback control of glucose feeding

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Cell growth and by-product formation in a pyruvate kinase mutant of E. coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Error-prone PCR of Vitreoscilla hemoglobin (VHb) to support the growth of microaerobic Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Novel hemoglobins to enhance microaerobic growth and substrate utilization in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Nitrite inhibition of Vitreoscilla hemoglobin (VHb) in recombinant E. coli: direct evidence that VHb enhances recombinant protein production

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Dissection of central carbon metabolism of hemoglobin-expressing Escherichia coli by 13C nuclear magnetic resonance flux distribution analysis in microaerobic bioprocesses.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

DNA microarray detection of metabolic responses to protein overproduction in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Kinetics of heat-shock response and inclusion body formation during temperature-induced production of basic fibroblast growth factor in high-cell-density cultures of recombinant Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Effects of FIS overexpression on cell growth, rRNA synthesis, and ribosome content in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Metabolic oscillations in an E. coli fermentation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Co-overexpression of RspAB improves recombinant protein production in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Towards the development of a minimal cell model by generalization of a model of Escherichia coli: use of dimensionless rate parameters

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Kinetic model of in vivo folding and inclusion body formation in recombinant Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Stochastic kinetic analysis of the Escherichia coli stress circuit using sigma(32)-targeted antisense

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Transgenic plants as factories for biopharmaceuticals

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Foreign protein production in plant tissue cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Producing proteins in transgenic plants and animals

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Characterization of monoclonal antibody fragments produced by plant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Glycoproteins from insect cells: sialylated or not?

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

N-glycan patterns of human transferrin produced in Trichoplusia ni insect cells: effects of mammalian galactosyltransferase.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Improved glycosylation of a foreign protein by Tn-5B1-4 cells engineered to express mammalian glycosyltransferases.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Novel baculovirus expression vectors that provide sialylation of recombinant glycoproteins in lepidopteran insect cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Production of a sialylated N-linked glycoprotein in insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Determination of nucleotides and sugar nucleotides involved in protein glycosylation by high-performance anion-exchange chromatography: sugar nucleotide contents in cultured insect cells and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

High-level expression and stabilization of recombinant human chitinase produced in a continuous constitutive Pichia pastoris expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Human insulin from a precursor overexpressed in the methylotrophic yeast Pichia pastoris and a simple procedure for purifying the expression product

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

A rational approach to improving productivity in recombinant Pichia pastoris fermentation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Cell cycle-dependent protein secretion by Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

The metabolic burden of the PGK1 and ADH2 promoter systems for heterologous xylanase production by Saccharomyces cerevisiae in defined medium.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Cell-free translation reconstituted with purified components

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Programmed Escherichia coli cell lysis by expression of cloned T4 phage lysis genes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Human chymotrypsinogen B production from Pichia pastoris by integrated development of fermentation and downstream processing. Part 2. Protein recovery

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

Choline-binding domain as a novel affinity tag for purification of fusion proteins produced in Pichia pastoris.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900300-2

7 January 2021

10.1016/S0958-1669(02)00300-2

Identifiers

DOI

1 reference

3 August 2017

1 reference