Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins (Q34610662)

24793136

3 August 2017

title

Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins (English)

1 reference

3 August 2017

1

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2 June 2020

Sevin Turcan

8

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Perry Palmedo

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Rameen Beroukhim

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2 June 2020

author name string

Travis Ian Zack

2

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2 June 2020

Luc G T Morris

3

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2 June 2020

Kan Lin

4

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2 June 2020

Ellen Hukkelhoven

5

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2 June 2020

Radhika Raheja

6

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2 June 2020

I-Li Tan

7

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2 June 2020

Selvaraju Veeriah

9

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2 June 2020

Shasha Meng

10

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2 June 2020

Agnes Viale

11

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Steven E Schumacher

12

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2 June 2020

Timothy A Chan

15

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language of work or name

English

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publication date

4 May 2014

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3 August 2017

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2 June 2020

volume

46

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issue

6

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2 June 2020

page(s)

588-594

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describes a project that uses

2 June 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Structure of parkin reveals mechanisms for ubiquitin ligase activation

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Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection

7 July 2018

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The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

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Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

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PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.

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The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cyclin D1/PRAD1 as a central target in oncogenesis

7 July 2018

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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

7 July 2018

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Lessons from hereditary colorectal cancer

7 July 2018

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Function of a human cyclin gene as an oncogene

7 July 2018

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A cell cycle regulator potentially involved in genesis of many tumor types

7 July 2018

1 reference

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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

7 July 2018

1 reference

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More powerful procedures for multiple significance testing

7 July 2018

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Checkpoint pathways come of age.

7 July 2018

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Cdk pathway: cyclin-dependent kinases and cyclin-dependent kinase inhibitors

26 October 2018

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12 December 2020

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

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12 December 2020

Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degradation in Saccharomyces cerevisiae

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Downregulation of Bax mRNA expression and protein stability by the E6 protein of human papillomavirus 16

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Identifiers

DOI

10.1038/NG.2981

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24793136%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 June 2020

0 references

1 reference

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2 June 2020

24793136

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