Recent advances in understanding NF-kappaB regulation (Q34616595)

3 August 2017

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title

Recent advances in understanding NF-kappaB regulation (English)

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3 August 2017

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David L Boone

1

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3 August 2017

Eric G Lee

2

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3 August 2017

Shon Libby

3

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3 August 2017

Paula J Gibson

4

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3 August 2017

Marcia Chien

5

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3 August 2017

Faye Chan

6

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3 August 2017

Michelle Madonia

7

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3 August 2017

Patrick R Burkett

8

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3 August 2017

Averil Ma

9

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3 August 2017

1 May 2002

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Inflammatory Bowel Diseases

3 August 2017

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3 August 2017

8

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3 August 2017

3

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3 August 2017

201-212

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Signal transduction through NF-kappa B.

3 August 2017

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Cytokine gene transcription by NF-kappa B family members in patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Role of NF-kappaB in immune and inflammatory responses in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A role for transcription factor NF-kappa B in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

IKKalpha controls formation of the epidermis independently of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Sodium butyrate inhibits histone deacetylation in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Signal transduction by tumor necrosis factor: the Parker B. Francis Lectureship

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The essential role of MEKK3 in TNF-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Characterization of XIAP-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Inhibition of JNK activation through NF-kappaB target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

NF-kappaB signaling pathways in mammalian and insect innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The smallest known non-avian theropod dinosaur

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

IRAK: a kinase associated with the interleukin-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Toll-like receptor family and signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Human Nod1 confers responsiveness to bacterial lipopolysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TRAF6 is a signal transducer for interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Autoimmunity and apoptosis: the Crohn's connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Global expression analysis of extracellular matrix-integrin interactions in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Isolation and characterization of two novel A20-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00054725-200205000-00008

10.1097/00054725-200205000-00008

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference