Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon. (Q34618385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon (English)

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5 January 2020

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GOA release 2020-03-11

author

Hongyan Wang

1

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5 January 2020

author name string

Yingshi Ouyang

2

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5 January 2020

W Gregory Somers

3

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5 January 2020

William Chia

4

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5 January 2020

Bingwei Lu

5

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5 January 2020

language of work or name

English

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publication date

1 September 2007

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5 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

449

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5 January 2020

issue

7158

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5 January 2020

page(s)

96-100

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aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

5 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Asymmetric and symmetric stem-cell divisions in development and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Polo-like kinases: a team in control of the division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Aberrant activation of notch signaling in human breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Polo-like kinases and the orchestration of cell division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Asymmetric cell division in the Drosophila nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

In vivo localisation of the mitotic POLO kinase shows a highly dynamic association with the mitotic apparatus during early embryogenesis in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

cdc2 links the Drosophila cell cycle and asymmetric division machineries

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

Asymmetric segregation of Numb and Prospero during cell division

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501

26 October 2018

Identifiers

DOI

10.1038/NATURE06056

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 January 2020

0 references

1 reference

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5 January 2020

PubMed publication ID

17805297

1 reference