Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells (Q34621046)

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English	Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells (English)

1 reference

Europe PubMed Central

3 August 2017

papillary thyroid cancer

1 reference

based on heuristic

inferred from title

Theodore S Nowicki

object named as

Theodore S Nowicki

1

0 references

Zbyszek Darzynkiewicz

object named as

Zbigniew Darzynkiewicz

3

0 references

2

object named as

Hong Zhao

1 reference

Europe PubMed Central

3 August 2017

author name string

Augustine Moscatello

4

1 reference

Europe PubMed Central

3 August 2017

Edward Shin

5

1 reference

Europe PubMed Central

3 August 2017

Stimson Schantz

6

1 reference

Europe PubMed Central

3 August 2017

Raj K Tiwari

7

1 reference

Europe PubMed Central

3 August 2017

Jan Geliebter

8

1 reference

Europe PubMed Central

3 August 2017

publication date

1 January 2011

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

10

1 reference

Europe PubMed Central

3 August 2017

1

1 reference

Europe PubMed Central

3 August 2017

100-107

1 reference

Europe PubMed Central

3 August 2017

New biomarkers probing depth of cell senescence assessed by laser scanning cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Increasing world incidence of thyroid cancer: increased detection or higher radiation exposure?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Inhibition of uPAR and uPA reduces invasion in papillary thyroid carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer

1 reference

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7 July 2018

PI3K/Akt signalling pathway specific inhibitors: a novel strategy to sensitize cancer cells to anti-cancer drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Regulation of cell signalling by uPAR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Pseudo-DNA damage response in senescent cells

1 reference

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7 July 2018

Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence

1 reference

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7 July 2018

Rapamycin decelerates cellular senescence

1 reference

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7 July 2018

A comparative analysis of the cell biology of senescence and aging

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Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases

1 reference

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7 July 2018

RNAi-mediated downregulation of urokinase plasminogen activator receptor inhibits proliferation, adhesion, migration and invasion in oral cancer cells

1 reference

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7 July 2018

RNAi therapeutics: an update on delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Down-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Differential expression of the components of the plasminogen activating system in human thyroid tumour derived cell lines and papillary carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Prolonged unbalanced growth induces cellular senescence markers linked with mechano transduction in normal and tumor cells

1 reference

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7 July 2018

BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

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7 July 2018

Interfering with cancer: a brief outline of advances in RNA interference in oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Second primary malignancies in thyroid cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

1 reference

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7 July 2018

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

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7 July 2018

Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Replicative senescence of human fibroblast-like cells in culture

1 reference

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7 July 2018

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048079

7 July 2018

Erythroid differentiation of Friend leukemia cells as studied by acridine orange staining and flow cytometry

1 reference

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7 July 2018

Total thyroidectomy plus neck dissection in differentiated papillary thyroid carcinoma patients: pattern of nodal metastasis, morbidity, recurrence, and postoperative levels of serum parathyroid hormone.

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.1.14362

21 January 2018

Correlation between the BRAF V600E mutation and tumor invasiveness in papillary thyroid carcinomas smaller than 20 millimeters: analysis of 1060 cases.

1 reference

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21 January 2018

A negative feedback signaling network underlies oncogene-induced senescence

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.1.14362

21 January 2018

When senescence masquerades as DNA damage: is DNA replication stress the culprit?

1 reference

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26 October 2018

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.1.14362

21 January 2018

Clinical implication of the number of central lymph node metastasis in papillary thyroid carcinoma: preliminary report

1 reference

https://pubmed.ncbi.nlm.nih.gov/21191179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

1 reference

https://pubmed.ncbi.nlm.nih.gov/21191179

12 December 2020

based on heuristic

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New cell cycle compartments identified by multiparameter flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21191179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Papillary and follicular thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21191179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CC.10.1.14362

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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