A comparative analysis of the cell biology of senescence and aging (Q37473186)

20 August 2017

1 reference

title

A comparative analysis of the cell biology of senescence and aging (English)

1 reference

20 August 2017

1 reference

Eun Seong Hwang

1

1 reference

20 August 2017

Gyesoon Yoon

series ordinal

2

1 reference

20 August 2017

Hyun Tae Kang

series ordinal

3

1 reference

20 August 2017

7 May 2009

1 reference

Cellular and Molecular Life Sciences

20 August 2017

1 reference

20 August 2017

66

1 reference

20 August 2017

2503-2524

1 reference

20 August 2017

15

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-009-0034-2

20 August 2017

0 references

cites work

Suppression of the chemically transformed phenotype of BHK cells by a human cDNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Integrin-linked kinase induces both senescence-associated alterations and extracellular fibronectin assembly in aging cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Lysosomes and oxidative stress in aging and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Decline with age of the respiratory chain activity in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Mitochondrial DNA mutations in human degenerative diseases and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Growth stimulation leads to cellular senescence when the cell cycle is blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Human aging is associated with stochastic somatic mutations of mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0034-2

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

21 January 2018

1 reference

12 December 2020

DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A.

1 reference

12 December 2020

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents

1 reference

12 December 2020

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

1 reference

12 December 2020

Cell size in aging monolayer cultures

1 reference

12 December 2020

The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

1 reference

12 December 2020

Role of intermediate filaments in migration, invasion and metastasis

1 reference

12 December 2020

Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

1 reference

12 December 2020

SA beta Gal staining: biomarker or delusion

1 reference

12 December 2020

Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro

1 reference

12 December 2020

The Effect of Age on Mitochondrial Ultrastructure

1 reference

12 December 2020

1 reference

12 December 2020

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

12 December 2020

Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

1 reference

12 December 2020

1 reference

12 December 2020

Ceramide induces expression of the senescence histochemical marker, beta-galactosidase, in human fibroblasts.

1 reference

12 December 2020

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

12 December 2020

Stimulation of Macroautophagy Can Rescue Older Cells from 8-OHdG mtDNA Accumulation: A Safe and Easy Way to Meet Goals in the SENS Agenda

1 reference

12 December 2020

TGF-beta cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence

1 reference

12 December 2020

On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes

1 reference

12 December 2020

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

12 December 2020

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

1 reference

12 December 2020

Morphological adjustment of senescent cells by modulating caveolin-1 status.

1 reference

12 December 2020

Role of focal adhesion kinase in integrin signaling

1 reference

12 December 2020

1 reference

12 December 2020

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

12 December 2020

Effects of the type of dietary fat at two levels of vitamin E in Wistar male rats during development and aging. IV. Biochemical and morphometric parameters of the heart

1 reference

12 December 2020

Fibroblasts cultured from venous ulcers display cellular characteristics of senescence

1 reference

12 December 2020

Intermediate filaments in the Sertoli cells of the ageing human testis

1 reference

12 December 2020

Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.

1 reference

12 December 2020

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

1 reference

12 December 2020

A continuous correlation between oxidative stress and telomere shortening in fibroblasts

1 reference

12 December 2020

Ultrastructural changes accompanying the aging of human diploid cells in culture

1 reference

12 December 2020

Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells

1 reference

12 December 2020

Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening.

1 reference

12 December 2020

Involvement of Rel/NF-kappa B transcription factors in senescence.

1 reference

12 December 2020

The limitations and validities of senescence associated-beta-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells

1 reference

12 December 2020

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

12 December 2020

Increased expression of mitochondrial transcription factor A and nuclear respiratory factor-1 in skeletal muscle from aged human subjects

1 reference

12 December 2020

Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts

1 reference

12 December 2020

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

12 December 2020

The promise and perils of Wnt signaling through beta-catenin.

1 reference

12 December 2020

Morpho-dynamic changes of mitochondria during ageing of human endothelial cells

1 reference

12 December 2020

Development of vimentin filaments in the cells of the articular disc of the rat squamosomandibular joint with age

1 reference

12 December 2020

Age-induced hypertrophy of astrocytes in rat supraoptic nucleus: a cytological, morphometric, and immunocytochemical study

1 reference

12 December 2020

Effects of age on glycogen synthase and phosphorylase activities in rat liver

1 reference

12 December 2020

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

1 reference

12 December 2020

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

1 reference

12 December 2020

Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

1 reference

12 December 2020

Evaluation of the activities of eight lysosomal hydrolases in sera of humans, rats and pigs of different ages

1 reference

12 December 2020

Immunohistochemical analysis of lens cells on formation of different types of age-related cataract in humans

1 reference

12 December 2020

Protein synthesis, posttranslational modifications, and aging

1 reference

12 December 2020

Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells

1 reference

12 December 2020

GSK-3: new thoughts on an old enzyme

1 reference

12 December 2020

Oxidants, oxidative stress and the biology of ageing

1 reference

12 December 2020

Activation of the human vimentin gene by the Tax human T-cell leukemia virus. I. Mechanisms of regulation by the NF-kappa B transcription factor.

1 reference

12 December 2020

Plasma fibronectin in French centenarians

1 reference

12 December 2020

Genomic instability in laminopathy-based premature aging

1 reference

12 December 2020

Senescence-associated beta-galactosidase histochemistry for the primate eye.

1 reference

12 December 2020

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

1 reference

12 December 2020

Intralysosomal iron: a major determinant of oxidant-induced cell death

1 reference

12 December 2020

Ultrastructure of the aging myocardium: a morphometric approach

1 reference

12 December 2020

Morphologic changes accompanying senescence of cultured human diploid cells

1 reference

12 December 2020

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

1 reference

12 December 2020

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

1 reference

12 December 2020

Growth Properties and Growth Factor Responsiveness in Skin Fibroblasts from Centenarians

1 reference

12 December 2020

Mitochondrial fission in apoptosis, neurodegeneration and aging

1 reference

12 December 2020

Cellular proliferation potential during aging and caloric restriction in rhesus monkeys (Macaca mulatta)

1 reference

12 December 2020

Tumour biology: senescence in premalignant tumours

1 reference

12 December 2020

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

1 reference

12 December 2020

Telomere-driven replicative senescence is a stress response

1 reference

12 December 2020

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

1 reference

12 December 2020

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

12 December 2020

Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells.

1 reference

12 December 2020

Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations

1 reference

12 December 2020

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.

1 reference

12 December 2020

Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts

1 reference

12 December 2020

Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts

1 reference

12 December 2020

Comparison by autoradiography of macromolecular biosynthesis in "young" and "old" human diploid fibroblast cultures. A brief note

1 reference

12 December 2020

Nuclear actin dynamics--from form to function

1 reference

12 December 2020

1 reference

12 December 2020

Characterization of residual bodies fromed in phase II cultivated human glia cells

1 reference

12 December 2020

Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells

1 reference

12 December 2020

Ageing and subcellular distribution of mitochondria: role of mitochondrial DNA deletions and energy production

1 reference

12 December 2020

Protein profiling of the human epidermis from the elderly reveals up-regulation of a signature of interferon-gamma-induced polypeptides that includes manganese-superoxide dismutase and the p85beta subunit of phosphatidylinositol 3-kinase

1 reference

12 December 2020

Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1

1 reference

12 December 2020

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

12 December 2020

Is beta-galactosidase staining a marker of senescence in vitro and in vivo?

1 reference

12 December 2020

Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts

1 reference

12 December 2020

Down-regulation of amphiphysin-1 is responsible for reduced receptor-mediated endocytosis in the senescent cells

1 reference

12 December 2020

The role of chondrocyte senescence in osteoarthritis

1 reference

12 December 2020

Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging

1 reference

12 December 2020

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

1 reference

12 December 2020

Premature ageing in mice expressing defective mitochondrial DNA polymerase

1 reference

12 December 2020

Cell Size and Nucleic Acid Content in the Diploid Human Cell Line WI-38 During Aging

1 reference

12 December 2020

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

1 reference

12 December 2020

Rapid induction of senescence in human cervical carcinoma cells

1 reference

12 December 2020

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

12 December 2020

Altered regulation of fibronectin gene expression in Werner syndrome fibroblasts

1 reference

12 December 2020

Lysosomal involvement in apoptosis

1 reference

12 December 2020

Oncogene-induced senescence as an initial barrier in lymphoma development

1 reference

12 December 2020

Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4,977 BP-deleted mitochondrial DNA.

1 reference

12 December 2020

MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress

1 reference

12 December 2020

Relationship between in vivo age and in vitro aging: assessment of 669 cell cultures derived from members of the Baltimore Longitudinal Study of Aging

1 reference

12 December 2020

Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase

1 reference

12 December 2020

Recent advances in the cell biology of aging

1 reference

12 December 2020

Overexpression of the vimentin gene in transgenic mice inhibits normal lens cell differentiation

1 reference

12 December 2020

Loss of linker histone H1 in cellular senescence

1 reference

12 December 2020

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

1 reference

12 December 2020

High-voltage electron microscopy of human diploid fibroblasts during ageing in vitro. Morphometric analysis of mitochondria

1 reference

12 December 2020

Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.

1 reference

12 December 2020

Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process.

1 reference

12 December 2020

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation

1 reference

12 December 2020

Early mitochondrial dysfunction in long-lived Mclk1+/- mice

1 reference

12 December 2020

Oncogene-induced cell senescence--halting on the road to cancer

1 reference

12 December 2020

Functional aging and gradual senescence in zebrafish

1 reference

12 December 2020

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

1 reference

12 December 2020

Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells

1 reference

12 December 2020

Wnt signalling and its impact on development and cancer

1 reference

12 December 2020

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

1 reference

12 December 2020

Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis

1 reference

12 December 2020

Genetic and functional changes in mitochondria associated with aging

1 reference

12 December 2020

The formation of enlarged and giant mitochondria in the aging process of human hepatic cells

1 reference

12 December 2020

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

1 reference

12 December 2020

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

12 December 2020

Glycogen accumulation in tibial nerves of experimentally diabetic and aging control rats

1 reference

12 December 2020

Senescence-associated alterations of cytoskeleton: extraordinary production of vimentin that anchors cytoplasmic p53 in senescent human fibroblasts

1 reference

12 December 2020

Low oxygen delays fibroblast senescence despite shorter telomeres

1 reference

12 December 2020

Cell senescence: hypertrophic arrest beyond the restriction point

1 reference

12 December 2020

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

1 reference

12 December 2020

Mitochondrial alterations in Parkinson's disease: new clues

1 reference

12 December 2020

Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes

1 reference

12 December 2020

DNA damage foci at dysfunctional telomeres

1 reference

12 December 2020

The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction

1 reference

12 December 2020

Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging.

1 reference

12 December 2020

Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys

1 reference

12 December 2020

Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence

1 reference

12 December 2020

Lysosomal enzyme activities in parenchymal and nonparenchymal liver cells isolated from young, adult and old rats.

1 reference

12 December 2020

Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide

1 reference

12 December 2020

Markers of senescence?

1 reference

12 December 2020

Growth factor responsiveness of cultured human fibroblasts declines with age

1 reference

12 December 2020

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

12 December 2020

Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

1 reference

12 December 2020

Are cross-bridging structures involved in the bundle formation of intermediate filaments and the decrease in locomotion that accompany cell aging?

1 reference

12 December 2020

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

1 reference

12 December 2020

Role of the intermediate filament protein vimentin in delaying senescence and in the spontaneous immortalization of mouse embryo fibroblasts.

1 reference

12 December 2020

Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence

1 reference

12 December 2020

Protein degradation in mitochondria: implications for oxidative stress, aging and disease: a novel etiological classification of mitochondrial proteolytic disorders.

1 reference

12 December 2020

Endogenous beta-galactosidase activity in continuously nonproliferating cells

1 reference

12 December 2020

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

12 December 2020

Identification and characterization of an increased glycoprotein in aging: age-associated translocation of cathepsin D.

1 reference

12 December 2020

Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung

1 reference

12 December 2020

Molecular dissection of formation of senescence-associated heterochromatin foci

1 reference

12 December 2020

Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles

1 reference

12 December 2020

Vimentin is the specific target in skin glycation. Structural prerequisites, functional consequences, and role in skin aging

1 reference

12 December 2020

Load-induced focal adhesion mechanotransduction is altered with aging in the Fischer 344/NNiaHSd x Brown Norway/BiNia rat aorta

1 reference

12 December 2020

Lamin A-dependent nuclear defects in human aging

1 reference

12 December 2020

Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts.

1 reference

12 December 2020

mTOR, translation initiation and cancer

1 reference

12 December 2020

Quantifying dense bodies and lipofuscin during aging: a morphologist's perspective.

1 reference

12 December 2020

Electron microscopy of human fibroblasts in tissue culture during logarithmic and confluent stages of growth

1 reference

12 December 2020

In vivo interaction between mitochondria carrying mtDNAs from different mouse species

1 reference

12 December 2020

Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells

1 reference

12 December 2020

Cellular senescence in aging primates.

1 reference

12 December 2020

Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages

1 reference

12 December 2020

Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis

1 reference

12 December 2020

How to live long and prosper: autophagy, mitochondria, and aging

1 reference

12 December 2020

Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation

1 reference

12 December 2020

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span

1 reference

12 December 2020

Lysosomal activity in the aging rat liver: II. Morphometry of acid phosphatase positive dense bodies

1 reference

12 December 2020

Cellular senescence, cancer and aging: the telomere connection

1 reference

12 December 2020

Lack of major mitochondrial bioenergetic changes in cultured skin fibroblasts from aged individuals.

1 reference

12 December 2020

Accumulation of senescent cells in mitotic tissue of aging primates

1 reference

12 December 2020

Glycogen accumulation of the aging human brain.

1 reference

12 December 2020

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

1 reference

12 December 2020

Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence

1 reference

12 December 2020

1 reference

12 December 2020

Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain

1 reference

12 December 2020

Does pH 6 beta-galactosidase activity indicate cell senescence?

1 reference

12 December 2020

Expression of endothelin, fibronectin, and mortalin as aging and mortality markers.

1 reference

12 December 2020

Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

1 reference

12 December 2020

Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts

1 reference

12 December 2020

Effect of age on liver protein synthesis and degradation

1 reference

12 December 2020

BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

12 December 2020

Nicotinamide extends replicative lifespan of human cells

1 reference

12 December 2020

The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes

1 reference

12 December 2020

Aging and nuclear organization: lamins and progeria

1 reference

12 December 2020

Effect of aging on glycogen synthesis in liver of starved-refed rats.

1 reference

12 December 2020

Liver mitochondrial respiratory functions decline with age

1 reference

12 December 2020

Mitochondrial dysfunction leads to telomere attrition and genomic instability

1 reference

12 December 2020

10.1007/S00018-009-0034-2

Identifiers

DOI

1 reference

release_wjy4ht3pg5d7jhzlnp6eyqfmqa

20 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wjy4ht3pg5d7jhzlnp6eyqfmqa

24 November 2022

mapped directly with Wikidata item

1 reference