Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling. (Q34621755)

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29 December 2019

title

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling (English)

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29 December 2019

4

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29 December 2019

author name string

Songcheng Zhu

series ordinal

1

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29 December 2019

Wei Wang

series ordinal

2

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29 December 2019

David C Clarke

series ordinal

3

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29 December 2019

language of work or name

English

0 references

publication date

23 April 2007

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Journal of Biological Chemistry

29 December 2019

published in

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29 December 2019

volume

282

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29 December 2019

issue

25

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29 December 2019

page(s)

18327-18338

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TGF-beta signal transduction

29 December 2019

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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Signal transduction by the TGF-beta superfamily

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

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Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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Smad transcription factors

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

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Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

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Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

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Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II

21 January 2018

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

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Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling

21 January 2018

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.

21 January 2018

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Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

21 January 2018

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Microtubule binding to Smads may regulate TGF beta activity

21 January 2018

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

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The mouse Mps1p-like kinase regulates centrosome duplication

21 January 2018

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Identification of novel protein-protein interactions using a versatile mammalian tandem affinity purification expression system

21 January 2018

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Generation of mammalian cells stably expressing multiple genes at predetermined levels.

21 January 2018

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Systems theory of Smad signalling.

21 January 2018

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The type II TGF-beta receptor signals diverse responses in cooperation with the type I receptor

21 January 2018

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The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

21 January 2018

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Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

21 January 2018

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Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores

21 January 2018

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Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

21 January 2018

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Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells

21 January 2018

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21 January 2018

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21 January 2018

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Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1.

21 January 2018

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Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

21 January 2018

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Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

21 January 2018

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

21 January 2018

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MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability

21 January 2018

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TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M700636200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452325%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference