Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes (Q34623312)

3 August 2017

Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes (English)

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3 August 2017

1

Branden D Tarlow

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3 August 2017

Markus Grompe

7

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author name string

Carl Pelz

2

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3 August 2017

Willscott E Naugler

3

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3 August 2017

Leslie Wakefield

4

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3 August 2017

Elizabeth M Wilson

5

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3 August 2017

Milton J Finegold

6

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3 August 2017

language of work or name

English

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publication date

9 October 2014

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3 August 2017

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3 August 2017

15

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3 August 2017

605-618

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3 August 2017

5

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describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4254170/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury

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Adult hepatocytes are generated by self-duplication rather than stem cell differentiation.

7 July 2018

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Hippo pathway activity influences liver cell fate

7 July 2018

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Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming.

7 July 2018

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Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury

7 July 2018

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The biliary epithelium gives rise to liver progenitor cells

7 July 2018

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The liver is a peculiar organ when it comes to stem cells

7 July 2018

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Rethinking differentiation: stem cells, regeneration, and plasticity

7 July 2018

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Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration.

7 July 2018

1 reference

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The epigenetics of epithelial-mesenchymal plasticity in cancer

7 July 2018

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Smoothened is a master regulator of adult liver repair

7 July 2018

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Robust cellular reprogramming occurs spontaneously during liver regeneration.

7 July 2018

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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

7 July 2018

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Cholangiocarcinomas can originate from hepatocytes in mice

7 July 2018

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Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

7 July 2018

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Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture

7 July 2018

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Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice.

7 July 2018

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Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential

7 July 2018

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The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

7 July 2018

1 reference

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Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation

7 July 2018

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The basics of epithelial-mesenchymal transition

7 July 2018

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Stem cells and liver regeneration.

7 July 2018

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Metaplasia and somatic cell reprogramming.

7 July 2018

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Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

7 July 2018

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Expression of nestin-green fluorescent protein transgene marks oval cells in the adult liver.

7 July 2018

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Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury

7 July 2018

1 reference

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Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells

7 July 2018

1 reference

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The origin and liver repopulating capacity of murine oval cells

7 July 2018

1 reference

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Kinetics of liver repopulation after bone marrow transplantation.

7 July 2018

1 reference

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The repopulation potential of hepatocyte populations differing in size and prior mitotic expansion

7 July 2018

1 reference

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Oval cell numbers in human chronic liver diseases are directly related to disease severity.

7 July 2018

1 reference

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Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes

7 July 2018

1 reference

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Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes

7 July 2018

1 reference

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Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat.

7 July 2018

1 reference

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Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.

7 July 2018

1 reference

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Neuroendocrine features of reactive bile ductules in cholestatic liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Is there a liver stem cell?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Hepatocytes, rather than cholangiocytes, can be the major source of primitive ductules in the chronically injured mouse liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Pancreatic acinar tissue in liver explants: a morphologic and immunohistochemical study

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Identification of adult hepatic progenitor cells capable of repopulating injured rat liver.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254170

A precursor-product relationship exists between oval cells and hepatocytes in rat liver

26 October 2018

1 reference

12 December 2020

Liver damage in the rat induces hepatocyte stem cells from biliary epithelial cells

1 reference

12 December 2020

Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease

1 reference

12 December 2020

1 reference

12 December 2020

Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver

1 reference

12 December 2020

N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas

1 reference

12 December 2020

10.1016/J.STEM.2014.09.008

Identifiers

DOI

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3 August 2017

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3 August 2017

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