Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins. (Q34624684)

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English	Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.	scientific article

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26 February 2020

Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins (English)

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26 February 2020

endoplasmic reticulum

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oligosaccharide

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26 February 2020

Sarah A. Allman

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26 February 2020

Spencer Williams

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26 February 2020

Terry D. Butters

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Terry D Butters

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26 February 2020

author name string

Nikolay V Kukushkin

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26 February 2020

Lorna Pierce

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26 February 2020

Raymond A Dwek

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publication date

16 March 2013

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26 February 2020

Cellular and Molecular Life Sciences

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26 February 2020

70

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26 February 2020

2799-2814

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26 February 2020

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26 February 2020

https://scigraph.springernature.com/pub.10.1007/s00018-013-1304-6

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Assembly of asparagine-linked oligosaccharides

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21 January 2018

Glycoprotein folding, quality control and ER-associated degradation

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21 January 2018

One step at a time: endoplasmic reticulum-associated degradation

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21 January 2018

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

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21 January 2018

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

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21 January 2018

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

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21 January 2018

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

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21 January 2018

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p

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21 January 2018

Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol

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21 January 2018

Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase.

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21 January 2018

Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides

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21 January 2018

Role of N-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation

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21 January 2018

Oligosaccharide transport: pumping waste from the ER into lysosomes

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21 January 2018

Intracellular functions of N-linked glycans

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21 January 2018

Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells

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21 January 2018

Different effects of the glucosidase inhibitors 1-deoxynojirimycin, N-methyl-1-deoxynojirimycin and castanospermine on the glycosylation of rat alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein

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21 January 2018

Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex

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21 January 2018

Processing of viral envelope glycoprotein by the endomannosidase pathway: evaluation of host cell specificity

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21 January 2018

Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling

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21 January 2018

Analyses of dolichol pyrophosphate-linked oligosaccharides in cell cultures and tissues by fluorophore-assisted carbohydrate electrophoresis

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21 January 2018

Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

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21 January 2018

Free oligosaccharide regulation during mammalian protein N-glycosylation.

1 reference

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21 January 2018

Colocalization of Ca2+-ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage

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21 January 2018

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

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21 January 2018

Checkpoints in ER-associated degradation: excuse me, which way to the proteasome?

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21 January 2018

Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells

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21 January 2018

Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells.

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21 January 2018

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

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21 January 2018

Complete genome sequences of Chandipura and Isfahan vesiculoviruses.

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21 January 2018

Mutants of vesicular stomatitis virus blocked at different stages in maturation of the viral glycoprotein

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21 January 2018

Role of the lectin VIP36 in post-ER quality control of human alpha1-antitrypsin

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21 January 2018

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

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21 January 2018

Defining the glycan destruction signal for endoplasmic reticulum-associated degradation

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21 January 2018

EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin

1 reference

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21 January 2018

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

1 reference

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21 January 2018

Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.

1 reference

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21 January 2018

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

1 reference

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21 January 2018

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

1 reference

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21 January 2018

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems

1 reference

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21 January 2018

Hepatoma secretory proteins migrate from rough endoplasmic reticulum to Golgi at characteristic rates

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21 January 2018

Overexpression of Man2C1 leads to protein underglycosylation and upregulation of endoplasmic reticulum-associated degradation pathway

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12 December 2020

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Cytosol-to-lysosome transport of free polymannose-type oligosaccharides. Kinetic and specificity studies using rat liver lysosomes

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12 December 2020

based on heuristic

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Effect of proteasome inhibitors on the release into the cytosol of free polymannose oligosaccharides from glycoproteins

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Golgi endo-alpha-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503623

12 December 2020

based on heuristic

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Drug action of thapsigargin on the Ca2+ pump protein of sarcoplasmic reticulum.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503623

12 December 2020

based on heuristic

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Endoplasmic reticulum-to-cytosol transport of free polymannose oligosaccharides in permeabilized HepG2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures of the N-linked oligosaccharides of Gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis

1 reference

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12 December 2020

based on heuristic

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Intracellular compartmentalization and degradation of free polymannose oligosaccharides released during glycoprotein biosynthesis.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps

1 reference

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12 December 2020

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Identifiers

10.1007/S00018-013-1304-6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23503623%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23503623%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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