E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors (Q34634278)

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21 February 2020

title

E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors (English)

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21 February 2020

9

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21 February 2020

author name string

Qi Xie

1

1 reference

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21 February 2020

Shengyi Peng

2

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21 February 2020

Li Tao

3

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21 February 2020

Haihe Ruan

4

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21 February 2020

Yanglu Yang

5

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21 February 2020

Tie-Mei Li

6

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21 February 2020

Ursula Adams

7

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21 February 2020

Songshu Meng

8

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21 February 2020

Meng-Qiu Dong

10

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21 February 2020

Zengqiang Yuan

11

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21 February 2020

language of work or name

English

0 references

publication date

24 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344604%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 February 2020

published in

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21 February 2020

volume

289

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21 February 2020

issue

49

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21 February 2020

page(s)

34205-34213

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FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function

21 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

ROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Post-translational regulation of FOXO.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

The E2F family and the role of E2F1 in apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Stressing the role of FoxO proteins in lifespan and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

E2F1 and c-Myc in cell growth and death.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Negative regulation of the forkhead transcription factor FKHR by Akt.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.587170

dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.587170

Therapeutic efficacy of E2F1 in pancreatic cancer correlates with TP73 induction.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256352

Tumor induction and tissue atrophy in mice lacking E2F-1

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25344604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25344604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crosstalk between p53 and FOXO transcription factors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25344604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.587170

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344604%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344604%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference