Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells (Q40651121)

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scientific article published on April 29, 2003

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English	Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells	scientific article published on April 29, 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Characterization of insulin inhibition of transactivation by a C-terminal fragment of the forkhead transcription factor Foxo1 in rat hepatoma cells (English)

1 reference

Europe PubMed Central

22 September 2017

Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells (English)

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

1 reference

based on heuristic

inferred from title

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

transcriptional activation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12724332

29 December 2023

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

author name string

Valerie Perrot

1

1 reference

Europe PubMed Central

22 September 2017

Matthew M. Rechler

2

1 reference

Europe PubMed Central

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29 December 2023

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publication date

29 April 2003

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full work available at URL

http://www.jbc.org/article/S0021925819751424/pdf

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29 December 2023

https://api.elsevier.com/content/article/PII:S0021925819751424?httpAccept=text/xml

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

https://api.elsevier.com/content/article/PII:S0021925819751424?httpAccept=text/plain

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

https://syndication.highwire.org/content/doi/10.1074/jbc.M212750200

1 reference

10.1074/JBC.M212750200

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29 December 2023

Journal of Biological Chemistry

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Europe PubMed Central

22 September 2017

278

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Europe PubMed Central

22 September 2017

28

1 reference

Europe PubMed Central

22 September 2017

26111-26119

1 reference

Europe PubMed Central

22 September 2017

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Five years on the wings of fork head

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Negative regulation of the forkhead transcription factor FKHR by Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Role of the forkhead transcription family member, FKHR, in thymocyte differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The forkhead transcription factor Foxo1 regulates adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin-regulated gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Dexamethasone stimulation of rat insulin-like growth factor binding protein-1 promoter activity involves multiple cis-elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes. Regulation of cell cycling as a downstream molecule of thrombopoietin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

The extended protein kinase C superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Phosphatidylinositol 3'-kinase and p70s6k are required for insulin but not bisperoxovanadium 1,10-phenanthroline (bpV(phen)) inhibition of insulin-like growth factor binding protein gene expression. Evidence for MEK-independent activation of mitogen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Roles of phosphorylation sites in regulating activity of the transcription factor Pho4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Nuclear transport and transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

PKC- Mediates Insulin Effects on Glucose Transport in Cultured Preadipocyte-Derived Human Adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

GAL4 fusion vectors for expression in yeast or mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Regulation of the insulin gene by glucose: stimulation of trans-activation potency of human PDX-1 N-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212750200

21 January 2018

FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter1

27

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

The Journal of Clinical Endocrinology and Metabolism

76

87

716

author name string

Bandyopadhyay

publication date

2002

1 reference

10.1074/JBC.M212750200

https://api.crossref.org/works/10.1074/JBC.M212750200

29 December 2023

Identifiers

10.1074/JBC.M212750200

1 reference

Europe PubMed Central

22 September 2017

1 reference

Europe PubMed Central

22 September 2017

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