Free fatty acid induces endoplasmic reticulum stress and apoptosis of β-cells by Ca2+/calpain-2 pathways (Q34635587)

3 August 2017

Free fatty acid induces endoplasmic reticulum stress and apoptosis of β-cells by Ca2+/calpain-2 pathways (English)

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3 August 2017

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endoplasmic reticulum

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author name string

Wei Cui

1

1 reference

3 August 2017

Jie Ma

2

1 reference

3 August 2017

Xingqin Wang

3

1 reference

3 August 2017

Wenjuan Yang

4

1 reference

3 August 2017

Jing Zhang

5

1 reference

3 August 2017

Qiuhe Ji

6

1 reference

3 August 2017

language of work or name

English

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publication date

20 March 2013

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3 August 2017

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3 August 2017

8

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3 August 2017

3

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3 August 2017

e59921

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Creative Commons Attribution 4.0 International

3 August 2017

start time

20 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

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Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

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Arsenic induces apoptosis of human umbilical vein endothelial cells through mitochondrial pathways

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Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women

21 January 2018

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A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation

21 January 2018

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12 December 2020

Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release

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Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans

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Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels

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10.1371/JOURNAL.PONE.0059921

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DOI

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3 August 2017

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3 August 2017

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