Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1 (Q34650735)

3 August 2017

Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1 (English)

1 reference

NISC Comparative Sequencing Program

3 August 2017

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1 reference

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7

object named as

NISC Comparative Sequencing Program

1 reference

3 August 2017

14

James C Mullikin

1 reference

3 August 2017

13

Tyra G Wolfsberg

1 reference

3 August 2017

Meghan L Rudd

1

1 reference

3 August 2017

Hassan Mohamed

2

1 reference

3 August 2017

Jessica C Price

3

1 reference

3 August 2017

Andrea J O'Hara

4

1 reference

3 August 2017

Matthieu Le Gallo

5

1 reference

3 August 2017

Mary Ellen Urick

6

1 reference

3 August 2017

Pedro Cruz

8

1 reference

3 August 2017

Suiyuan Zhang

9

1 reference

3 August 2017

Nancy F Hansen

10

1 reference

3 August 2017

Andrew K Godwin

11

1 reference

3 August 2017

Dennis C Sgroi

12

1 reference

3 August 2017

Maria J Merino

15

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3 August 2017

Daphne W Bell

16

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3 August 2017

language of work or name

English

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publication date

26 November 2014

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3 August 2017

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3 August 2017

14

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3 August 2017

884

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https://scigraph.springernature.com/pub.10.1186/1471-2407-14-884

3 August 2017

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7 July 2018

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Type I and II endometrial cancers: have they different risk factors?

7 July 2018

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7 July 2018

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

7 July 2018

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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

7 July 2018

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Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers

7 July 2018

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Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

7 July 2018

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Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.

7 July 2018

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Uterine papillary serous cancer: a review of the literature

7 July 2018

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Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.

7 July 2018

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

7 July 2018

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Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis.

7 July 2018

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Adjuvant treatment for early-stage endometrial cancer

7 July 2018

1 reference

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Exome sequencing identifies GRIN2A as frequently mutated in melanoma

7 July 2018

1 reference

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DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation

7 July 2018

1 reference

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The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin

7 July 2018

1 reference

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Emerging therapeutic targets in endometrial cancer

7 July 2018

1 reference

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Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.

7 July 2018

1 reference

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Regulation of Ack1 localization and activity by the amino-terminal SAM domain

7 July 2018

1 reference

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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

7 July 2018

1 reference

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Clear cell carcinoma of the endometrium: a biological and clinical enigma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Shepherding AKT and androgen receptor by Ack1 tyrosine kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

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7 July 2018

1 reference

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HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Drug-sensitive FGFR2 mutations in endometrial carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation

7 July 2018

1 reference

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Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Function of discoidin domain receptor I in HGF-induced branching tubulogenesis of MDCK cells in collagen gel.

7 July 2018

1 reference

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Crystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1

7 July 2018

1 reference

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

7 July 2018

1 reference

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Discoidin domain receptor 1 controls growth and adhesion of mesangial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Cancer. Addiction to oncogenes--the Achilles heal of cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Mutations of the BRAF gene in human cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Tyrosine kinase activity of discoidin domain receptor 1 is necessary for smooth muscle cell migration and matrix metalloproteinase expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Discoidin domain receptor 1 isoform-a (DDR1alpha) promotes migration of leukocytes in three-dimensional collagen lattices

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Clear-cell and papillary serous cancer: treatment options

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Theories of endometrial carcinogenesis: a multidisciplinary approach

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Discoidin domain receptors: structural relations and functional implications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Epidemiology of cancer of the endometrium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

KLE: a cell line with defective estrogen receptor derived from undifferentiated endometrial cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Studies of the growth and cytogenetic properties of human endometrial adenocarcinoma in culture and its development into an established line

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Clear cell carcinoma of the endometrium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Human endometrial cancer cell cultures for hormonal studies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258955

Characterization of a new human endometrial carcinoma (RL95-2) established in tissue culture

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-14-884

21 January 2018

Identifiers

DOI

10.1186/1471-2407-14-884

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference