Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene (Q34650989)

3 August 2017

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title

Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene (English)

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3 August 2017

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Takao Senda

1

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3 August 2017

Atsushi Shimomura

series ordinal

2

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3 August 2017

Akiko Iizuka-Kogo

series ordinal

3

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3 August 2017

1 September 2005

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Anatomical Science International

3 August 2017

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3 August 2017

80

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3 August 2017

3

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3 August 2017

121-131

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https://scigraph.springernature.com/pub.10.1111/j.1447-073x.2005.00106.x

3 August 2017

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cites work

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Localization of the gene for familial adenomatous polyposis on chromosome 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Neuronal localization of the Adenomatous polyposis coli tumor suppressor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

A genetic model for colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Identification and characterization of the familial adenomatous polyposis coli gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The molecular basis of Turcot's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Identification of a link between the tumour suppressor APC and the kinesin superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Asef, a link between the tumor suppressor APC and G-protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Beta-catenin as oncogene: the smoking gun.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The APC tumour suppressor has a nuclear export function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The tumor suppressor protein APC colocalizes with beta-catenin in the colon epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Localization of the adenomatous polyposis coli tumour suppressor protein in the mouse central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

The colorectal tumour suppressor APC is present in the NMDA-receptor-PSD-95 complex in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1447-073X.2005.00106.X

10.1111/J.1447-073X.2005.00106.X

21 January 2018

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3 August 2017

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1 reference