Molecular mechanism of TGF-β signaling pathway in colon carcinogenesis and status of curcumin as chemopreventive strategy. (Q34660663)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24668546%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Molecular mechanism of TGF-β signaling pathway in colon carcinogenesis and status of curcumin as chemopreventive strategy (English)

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12 March 2020

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Nageswaran Sivalingam

series ordinal

2

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12 March 2020

author name string

Ganesan Ramamoorthi

series ordinal

1

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12 March 2020

publication date

26 March 2014

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12 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24668546%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

35

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12 March 2020

issue

8

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12 March 2020

page(s)

7295-7305

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Role of curcumin in cancer therapy

12 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin therapeutic promises and bioavailability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Republished: obesity and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

[Gender-specific influences on incidence, screening, treatment, and outcome of colorectal cancer].

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Modifiable risk factors for colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Colorectal cancer: genetics of development and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Role of transforming growth factor Beta in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF-beta signaling in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

The dynamic roles of TGF-β in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF-β signaling pathway and breast cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF-beta signaling alterations and susceptibility to colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF-beta signalling in colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Signaling of transforming growth factor-beta family members through Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

How cells read TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

TGF-beta signaling by Smad proteins

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

21 January 2018

12 December 2020

Microtubule binding to Smads may regulate TGF beta activity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Complexities of TGF-β targeted cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Differential modulation of cyclin gene expression by MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Mechanisms of TGF-beta-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Type III TGF-β receptor enhances colon cancer cell migration and anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

The potential role of TGFbeta1, TGFbeta2 and TGFbeta3 protein expression in colorectal carcinomas. Correlation with classic histopathologic factors and patient survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Antimetastatic role of Smad4 signaling in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Loss of Smad signaling in human colorectal cancer is associated with advanced disease and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin derivatives: molecular basis of their anti-cancer activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin in various cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin in Cancer Chemoprevention: Molecular Targets, Pharmacokinetics, Bioavailability, and Clinical Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Dose escalation of a curcuminoid formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin for chemoprevention of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Aberrant rel/nfkb genes and activity in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Molecular mechanisms of chemopreventive phytochemicals against gastroenterological cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Curcumin inhibits transforming growth factor-β1-induced EMT via PPARγ pathway, not Smad pathway in renal tubular epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1840-1

Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer

21 January 2018

1 reference

12 December 2020

Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis

1 reference

12 December 2020

Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.

1 reference

12 December 2020

Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas.

1 reference

12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

12 December 2020

Genomic instability and colon carcinogenesis: from the perspective of genes

1 reference

12 December 2020

Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line

1 reference

12 December 2020

High levels of transforming growth factor beta 1 correlate with disease progression in human colon cancer

1 reference

12 December 2020

Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound

1 reference

12 December 2020

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

1 reference

12 December 2020

Smad regulation in TGF-beta signal transduction

1 reference

12 December 2020

Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells

1 reference

12 December 2020

Curcumin inhibits TGF-β1-induced MMP-9 and invasion through ERK and Smad signaling in breast cancer MDA- MB-231 cells.

1 reference

12 December 2020

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

1 reference

12 December 2020

The TGF beta receptor activation process: an inhibitor- to substrate-binding switch

1 reference

12 December 2020

SMAD4/DPC4 expression and prognosis in human colorectal cancer

1 reference

12 December 2020

Diabetes mellitus and cancer risk: pooled analysis of eight cohort studies in Japan

1 reference

12 December 2020

Role of TGF-beta1, its receptor TGFbetaRII, and Smad proteins in the progression of colorectal cancer

1 reference

12 December 2020

Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21waf1 induction are important early events

1 reference

12 December 2020

10.1007/S13277-014-1840-1

Identifiers

DOI

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Dimensions Publication ID

12 March 2020

1024034916

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