Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells. (Q34661115)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712465%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells (English)

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13 March 2020

main subject

phenotypic plasticity

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author

Shohei Hori

series ordinal

1

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13 March 2020

author name string

Shohei Hori

series ordinal

1

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3 August 2017

publication date

1 May 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712465%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

published in

Immunological Reviews

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13 March 2020

volume

259

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13 March 2020

issue

1

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13 March 2020

page(s)

159-172

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Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells

13 March 2020

cites work

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Control of T-cell activation by CD4+ CD25+ suppressor T cells

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Control of regulatory T cell development by the transcription factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

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Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

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Regulatory T cells in nonlymphoid tissues

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Stability of regulatory T-cell lineage.

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Regulatory T cells: mechanisms of differentiation and function

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Phenotypical and functional specialization of FOXP3+ regulatory T cells

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Plasticity of CD4(+) FoxP3(+) T cells

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Physiologic control of the functional status of Foxp3+ regulatory T cells

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Developmental plasticity of murine and human Foxp3(+) regulatory T cells

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Regulatory T cells: stability revisited

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Regulatory T cell plasticity: beyond the controversies.

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The plasticity and stability of regulatory T cells.

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Human T regulatory cell therapy: take a billion or so and call me in the morning

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Regulatory T cells in stem cell transplantation: strategies and first clinical experiences.

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

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CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations.

21 January 2018

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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

21 January 2018

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Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment

21 January 2018

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Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

21 January 2018

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In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

21 January 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

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Epigenetic control of the foxp3 locus in regulatory T cells

21 January 2018

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DNA methylation controls Foxp3 gene expression

21 January 2018

1 reference

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

21 January 2018

1 reference

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

21 January 2018

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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

21 January 2018

1 reference

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

21 January 2018

1 reference

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

21 January 2018

1 reference

Regulatory T cell development in the absence of functional Foxp3.

21 January 2018

1 reference

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

21 January 2018

1 reference

Transcription factor Foxp3 and its protein partners form a complex regulatory network

21 January 2018

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Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification

21 January 2018

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Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

21 January 2018

1 reference

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

21 January 2018

1 reference

Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo

21 January 2018

1 reference

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

21 January 2018

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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

21 January 2018

1 reference

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

21 January 2018

1 reference

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

21 January 2018

1 reference

Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease

21 January 2018

1 reference

T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

21 January 2018

1 reference

Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R

21 January 2018

1 reference

Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells

21 January 2018

1 reference

OX40 costimulation turns off Foxp3+ Tregs.

21 January 2018

1 reference

Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice

21 January 2018

1 reference

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.

21 January 2018

1 reference

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

21 January 2018

1 reference

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

1 reference

Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

21 January 2018

1 reference

DC activated via dectin-1 convert Treg into IL-17 producers

21 January 2018

1 reference

IL-17-producing human peripheral regulatory T cells retain suppressive function

21 January 2018

1 reference

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

21 January 2018

1 reference

IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis

21 January 2018

1 reference

Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

21 January 2018

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Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

21 January 2018

1 reference

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

21 January 2018

1 reference

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

1 reference

T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells

21 January 2018

1 reference

Stability of the regulatory T cell lineage in vivo.

21 January 2018

1 reference

Developmental plasticity of Foxp3+ regulatory T cells

21 January 2018

1 reference

Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

21 January 2018

1 reference

CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

21 January 2018

1 reference

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

21 January 2018

1 reference

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease.

21 January 2018

1 reference

The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3

21 January 2018

1 reference

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

21 January 2018

1 reference

Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells

21 January 2018

1 reference

Single-cell analysis of the human T regulatory population uncovers functional heterogeneity and instability within FOXP3+ cells.

21 January 2018

1 reference

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

21 January 2018

1 reference

IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease

21 January 2018

1 reference

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

21 January 2018

1 reference

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

1 reference

Control of TH17 cells occurs in the small intestine.

21 January 2018

1 reference

Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity.

21 January 2018

1 reference

Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma

21 January 2018

1 reference

Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.

21 January 2018

1 reference

Coordination of early protective immunity to viral infection by regulatory T cells

21 January 2018

1 reference

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

21 January 2018

1 reference

A two-step process for thymic regulatory T cell development.

21 January 2018

1 reference

Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.

21 January 2018

1 reference

Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice

21 January 2018

1 reference

Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals

21 January 2018

1 reference

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

21 January 2018

1 reference

Stem cell states, fates, and the rules of attraction

21 January 2018

1 reference

Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways

21 January 2018

1 reference

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

21 January 2018

1 reference

Foxp3-dependent programme of regulatory T-cell differentiation

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712465%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference