STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease. (Q36231545)

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English	STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease.	scientific article

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12 February 2020

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease (English)

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12 February 2020

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12 February 2020

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Shoba Amarnath

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12 February 2020

Jacopo Mariotti

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12 February 2020

Yong Chan Kim

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12 February 2020

Jason Foley

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12 February 2020

Michael Eckhaus

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12 February 2020

John J O'Shea

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12 February 2020

Daniel H Fowler

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1 August 2012

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12 February 2020

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12 February 2020

37

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12 February 2020

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12 February 2020

209-222

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12 February 2020

CD4(+)Foxp3(+) regulatory T cell therapy in transplantation

1 reference

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1 October 2017

IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo

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1 October 2017

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

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1 October 2017

Regulatory T cells: history and perspective

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1 October 2017

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

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1 October 2017

Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I

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1 October 2017

Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

1 reference

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1 October 2017

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses

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1 October 2017

Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.

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1 October 2017

Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.

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1 October 2017

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

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1 October 2017

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

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1 October 2017

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

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1 October 2017

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

1 reference

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1 October 2017

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

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1 October 2017

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.

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1 October 2017

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

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1 October 2017

IL-17 contributes to CD4-mediated graft-versus-host disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.

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1 October 2017

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

Th17: the third member of the effector T cell trilogy

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1 October 2017

Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

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1 October 2017

Epigenetic control of the foxp3 locus in regulatory T cells

1 reference

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1 October 2017

Nonredundant roles for Stat5a/b in directly regulating Foxp3

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1 October 2017

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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1 October 2017

Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response

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1 October 2017

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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1 October 2017

Clinical application of expanded CD4+25+ cells

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1 October 2017

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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1 October 2017

CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

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1 October 2017

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

1 October 2017

Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets

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1 October 2017

Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program

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1 October 2017

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

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29 June 2018

Stability of the regulatory T cell lineage in vivo.

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29 June 2018

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

1 reference

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29 June 2018

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

1 reference

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22 September 2018

CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441059

22 September 2018

IL-27 inhibits the development of regulatory T cells via STAT3

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21 October 2018

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

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21 October 2018

The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22921119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human regulatory T cells control xenogeneic graft-versus-host disease induced by autologous T cells in RAG2-/-gammac-/- immunodeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22921119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22921119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22921119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22921119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.IMMUNI.2012.05.027

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12 February 2020

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12 February 2020

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12 February 2020

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