Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD. (Q34661769)

3 August 2017

title

Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD. (English)

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ORCID Public Data File 2021

3 August 2017

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author name string

Lu Y

1

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3 August 2017

Kitaura J

2

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3 August 2017

Oki T

3

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3 August 2017

Komeno Y

4

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3 August 2017

Ozaki K

5

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3 August 2017

Kiyono M

6

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3 August 2017

Kumagai H

7

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3 August 2017

Nakajima H

8

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3 August 2017

Nosaka T

9

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3 August 2017

Aburatani H

10

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3 August 2017

Kitamura T

11

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3 August 2017

publication date

9 August 2007

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3 August 2017

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3 August 2017

volume

21

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3 August 2017

issue

11

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3 August 2017

page(s)

2246-2257

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Induction of TSC-22 by treatment with a new anti-cancer drug, vesnarinone, in a human salivary gland cancer cell

3 August 2017

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Mechanism of apoptotic cell death of human gastric carcinoma cells mediated by transforming growth factor beta

21 January 2018

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Integrin alphaIIbbeta3 induces the adhesion and activation of mast cells through interaction with fibrinogen.

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Over-expression of TSC-22 (TGF-beta stimulated clone-22) markedly enhances 5-fluorouracil-induced apoptosis in a human salivary gland cancer cell line

21 January 2018

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A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

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7 January 2021

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells

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7 January 2021

Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

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7 January 2021

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

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7 January 2021

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

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7 January 2021

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

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7 January 2021

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

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7 January 2021

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

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7 January 2021

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

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7 January 2021

Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

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7 January 2021

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

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7 January 2021

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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7 January 2021

Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

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7 January 2021

The role of FLT3 in haematopoietic malignancies

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7 January 2021

Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse

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7 January 2021

FLT3: ITDoes matter in leukemia

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7 January 2021

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

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7 January 2021

Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter

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7 January 2021

Cloning of the human homologue of the TGF beta-stimulated clone 22 gene

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7 January 2021

Cloning of rat Sertoli cell follicle-stimulating hormone primary response complementary deoxyribonucleic acid: regulation of TSC-22 gene expression

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7 January 2021

Fibroblast growth factor downregulates expression of a basic helix-loop-helix-type transcription factor, scleraxis, in a chondrocyte-like cell line, TC6.

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7 January 2021

Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation

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7 January 2021

Non-stoichiometric reduced complexity probes for cDNA arrays

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7 January 2021

Dynamic expression of TSC-22 at sites of epithelial-mesenchymal interactions during mouse development.

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7 January 2021

Expression of TGF-beta stimulated clone-22 (TSC-22) in mouse development and TGF-beta signalling.

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7 January 2021

Nuclear translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator

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7 January 2021

Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3).

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7 January 2021

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

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7 January 2021

Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

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7 January 2021

RNAi-induced down-regulation of FLT3 expression in AML cell lines increases sensitivity to MLN518.

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7 January 2021

Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity

1 reference

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7 January 2021

Targeted inhibition of FLT3 overcomes the block to myeloid differentiation in 32Dcl3 cells caused by expression of FLT3/ITD mutations

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7 January 2021

Downregulation of putative tumor suppressor gene TSC-22 in human brain tumors

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7 January 2021

Differential expression of TGFbeta-stimulated clone 22 in normal prostate and prostate cancer

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7 January 2021

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

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7 January 2021

Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation

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7 January 2021

Retinoids and myelomonocytic growth factors cooperatively activate RARA and induce human myeloid leukemia cell differentiation via MAP kinase pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404883

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Dimensions Publication ID

3 August 2017

1006127703

0 references

1 reference