New approaches to the design and discovery of therapies to prevent erectile dysfunction (Q34664336)

3 August 2017

1 reference

title

New approaches to the design and discovery of therapies to prevent erectile dysfunction (English)

1 reference

3 August 2017

Haroldo A Toque

1

1 reference

PubMed ID

25195695

3 August 2017

Robert William Caldwell

series ordinal

2

1 reference

PubMed ID

25195695

3 August 2017

language of work or name

English

0 references

publication date

6 September 2014

1 reference

Expert Opinion on Drug Discovery

3 August 2017

1 reference

3 August 2017

9

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3 August 2017

12

1 reference

3 August 2017

1447-1469

1 reference

Evaluation and treatment of erectile dysfunction.

3 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Phosphodiesterase type 5 inhibitors for erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Pre-penile arteries are dominant in the regulation of penile vascular resistance in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Erectile dysfunction: anatomical parameters, etiology, diagnosis, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Neural control of erection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

PIP3EA and PD-168077, two selective dopamine D4 receptor agonists, induce penile erection in male rats: site and mechanism of action in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Physiology of penile erection and pathophysiology of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Nitric oxide and penile erectile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Role of nitric oxide and endothelium-derived hyperpolarizing factor (EDHF) in the regulation of blood pressure by leptin in lean and obese rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Distribution and factors associated with four premature ejaculation syndromes in outpatients complaining of ejaculating prematurely

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Sexual behaviour and dysfunction and help-seeking patterns in adults aged 40-80 years in the urban population of Asian countries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Sexual activity and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Influence of age and changes over time on erectile dysfunction: results from two large cross-sectional surveys 11 years apart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

One patient out of four with newly diagnosed erectile dysfunction is a young man--worrisome picture from the everyday clinical practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Emerging tools for erectile dysfunction: a role for regenerative medicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The artery size hypothesis: a macrovascular link between erectile dysfunction and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

All men with vasculogenic erectile dysfunction require a cardiovascular workup

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

SOP conservative (medical and mechanical) treatment of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Concomitant use of sildenafil and a vacuum entrapment device for the treatment of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone regulates smooth muscle contractile pathways in the rat prostate: emphasis on PDE5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Extracorporeally induced destruction of kidney stones by shock waves.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Extracorporeal shock wave lithotripsy of large difficult common bile duct stones: efficacy and analysis of factors that favor stone fragmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Extracorporeal shock waves improve angiogenesis after full thickness burn

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Low-intensity shock wave therapy and its application to erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Evaluation of the effect of different doses of low energy shock wave therapy on the erectile function of streptozotocin (STZ)-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Shockwave treatment of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Tadalafil once daily and extracorporeal shock wave therapy in the management of patients with Peyronie's disease and erectile dysfunction: results from a prospective randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Molecular pathophysiology and gene therapy of aging-related erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

State-of-the-art gene-based therapies: the road ahead

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Antisense and short hairpin RNA (shRNA) constructs targeting PIN (Protein Inhibitor of NOS) ameliorate aging-related erectile dysfunction in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Cloning of rat and human inducible penile nitric oxide synthase. Application for gene therapy of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Nitric oxide synthase gene transfer for erectile dysfunction in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase II deletion increases corpora cavernosa relaxation in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Oxidative stress in vascular disease and its pharmacological prevention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Superoxide dismutases: role in redox signaling, vascular function, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Growth factor therapy and neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The effect of vascular endothelial growth factor and adeno-associated virus mediated brain derived neurotrophic factor on neurogenic and vasculogenic erectile dysfunction induced by hyperlipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Dysregulation of cGMP-dependent protein kinase 1 (PKG-1) impairs erectile function in diabetic rats: influence of in vivo gene therapy of PKG1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Diabetes-induced coronary vascular dysfunction involves increased arginase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Role of apoptosis in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Stem and endothelial progenitor cells in erection biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Endothelial cell transplantation into the corpus cavernosum: moving towards cell-based gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Effect of mesenchymal stem cells associated to matrixen on the erectile function in the rat model with bilateral cavernous nerve crushing injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Adenoviral gene transfer of eNOS: high-level expression in ex vivo expanded marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Combined strategy of mesenchymal stem cell injection with vascular endothelial growth factor gene therapy for the treatment of diabetes-associated erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Cavernous nerve injury using rodent animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Emerging neuromodulatory molecules for the treatment of neurogenic erectile dysfunction caused by cavernous nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Treatment of erectile dysfunction in the obese type 2 diabetic ZDF rat with adipose tissue-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

VEGF improves survival of mesenchymal stem cells in infarcted hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Correction of diabetic erectile dysfunction with adipose derived stem cells modified with the vascular endothelial growth factor gene in a rodent diabetic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Combined therapeutic effect of udenafil and adipose-derived stem cell (ADSC)/brain-derived neurotrophic factor (BDNF)-membrane system in a rat model of cavernous nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone and phosphodiesterase type-5 inhibitors: new strategy for preventing endothelial damage in internal and sexual medicine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone partially ameliorates metabolic profile and erectile responsiveness to PDE5 inhibitors in an animal model of male metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Comparison of long-acting testosterone undecanoate formulation versus testosterone enanthate on sexual function and mood in hypogonadal men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Sildenafil increases serum testosterone levels by a direct action on the testes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The role of testosterone in erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Testosterone replacement therapy with long-acting testosterone undecanoate improves sexual function and quality-of-life parameters vs. placebo in a population of men with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The response to testosterone undecanoate in men with type 2 diabetes is dependent on achieving threshold serum levels (the BLAST study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Late-onset hypogonadism and mortality in aging men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

L-arginine transporters in cardiovascular disease: a novel therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Recent advances in arginine metabolism: roles and regulation of the arginases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Therapeutic use of citrulline in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Oral L-citrulline supplementation improves erectile function and penile structure in castrated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Activators of soluble guanylate cyclase for the treatment of male erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

NO-independent, haem-dependent soluble guanylate cyclase stimulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

BAY 41-2272: a stimulator of soluble guanylyl cyclase induces nitric oxide-dependent penile erection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Effects of the sGC stimulator BAY 41-2272 are not mediated by phosphodiesterase 5 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Synergistic effects of BAY 60-4552 and vardenafil on relaxation of corpus cavernosum tissue of patients with erectile dysfunction and clinical phosphodiesterase type 5 inhibitor failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The sGC activator BAY 60-2770 has potent erectile activity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

RhoA/Rho-kinase: a novel player in the regulation of penile erection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Rho kinase: an important mediator of atherosclerosis and vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

ROCKs as therapeutic targets in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

RhoA-mediated Ca2+ sensitization in erectile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Rho-kinase inhibition improves erectile function in aging male Brown-Norway rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Y-27632 improves the erectile dysfunction with ageing in SD rats through adjusting the imbalance between nNo and the Rho-kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Chronic administration of an oral Rho kinase inhibitor prevents the development of vasculogenic erectile dysfunction in a rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Novel strategies for inhibition of the p38 MAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathway to E-selectin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

MAP kinase 1/2 (Erk 1/2) and serine/threonine specific protein kinase Akt/PKB expression and activity in the human corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginine metabolism: nitric oxide and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase pathway in human endothelial cells in pathophysiological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Definitions/epidemiology/risk factors for sexual dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Erectile dysfunction, depression, and ischemic heart disease: does the existence of one component of this triad necessitate inquiring the other two?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Type 1 and Type 2 diabetic-erectile dysfunction: same diagnosis (ICD-9), different disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Prevalence and risk factors for erectile dysfunction in 2869 men using a validated questionnaire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Metabolic syndrome and erectile dysfunction among obese non-diabetic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Diabetes-induced vascular dysfunction involves arginase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase-boronic acid complex highlights a physiological role in erectile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase alteration in the reproductive system of alloxan-diabetic dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Endothelial control of vascular tone in large and small coronary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Oral L-arginine improves endothelial dysfunction in patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Incidence of erectile dysfunction in 800 hypertensive patients: a multicenter Egyptian national study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Arginase 1 mediates increased blood pressure and contributes to vascular endothelial dysfunction in deoxycorticosterone acetate-salt hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Possible role of bradykinin and angiotensin II in the regulation of penile erection and detumescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

A nitric oxide-releasing PDE5 inhibitor relaxes human corpus cavernosum in the absence of endogenous nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Does Low Intensity Extracorporeal Shock Wave Therapy Have a Physiological Effect on Erectile Function? Short-Term Results of a Randomized, Double-Blind, Sham Controlled Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

Summary of the Recommendations on Sexual Dysfunctions in Men

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.949234

10.1517/17460441.2014.949234

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

25195695