Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance (Q34667185)

3 August 2017

Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance (English)

1 reference

3 August 2017

1

1 reference

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12 June 2020

Lee Ratner

series ordinal

4

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12 June 2020

author name string

Xiaogang Cheng

series ordinal

2

1 reference

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12 June 2020

Rashmi Ramani

series ordinal

3

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12 June 2020

publication date

18 December 2014

1 reference

3 August 2017

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12 June 2020

volume

17

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12 June 2020

issue

1

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12 June 2020

page(s)

98-106

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describes a project that uses

12 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4297224/fullTextXML

inferred from PubMed Central ID database lookup

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7 July 2018

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7 July 2018

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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

7 July 2018

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Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.

7 July 2018

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Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation

7 July 2018

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Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

7 July 2018

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HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation

7 July 2018

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Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

7 July 2018

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The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

7 July 2018

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SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons

7 July 2018

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Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase

7 July 2018

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SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

7 July 2018

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A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest

7 July 2018

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Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac

7 July 2018

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HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

7 July 2018

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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

7 July 2018

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

7 July 2018

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

7 July 2018

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Inhibition of proliferation and differentiation and promotion of apoptosis by cyclin L2 in mouse embryonic carcinoma P19 cells

7 July 2018

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Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

7 July 2018

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7 July 2018

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Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.

7 July 2018

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Overexpression of cyclin L2 induces apoptosis and cell-cycle arrest in human lung cancer cells.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Familial Aicardi-Goutières syndrome due toSAMHD1mutations is associated with chronic arthropathy and contractures

26 October 2018

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SAMHD1: a new gene for CLL

26 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25532805

12 December 2020

inferred from PubMed ID database lookup

Cyclin T1 but not cyclin T2a is induced by a post-transcriptional mechanism in PAMP-activated monocyte-derived macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25532805

12 December 2020

inferred from PubMed ID database lookup

HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25532805

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CHOM.2014.11.009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25532805%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25532805%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference