Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells (Q34714647)

4 August 2017

Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells (English)

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4 August 2017

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Emelie Karnevi

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4 August 2017

Katarzyna Said

series ordinal

2

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4 August 2017

Roland Andersson

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3

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4 August 2017

Ann H Rosendahl

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4

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4 August 2017

language of work or name

English

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publication date

10 May 2013

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4 August 2017

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4 August 2017

13

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4 August 2017

235

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https://scigraph.springernature.com/pub.10.1186/1471-2407-13-235

4 August 2017

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cites work

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Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway

7 July 2018

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Celecoxib synergizes human pancreatic ductal adenocarcinoma cells to sorafenib-induced growth inhibition

7 July 2018

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Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells

7 July 2018

1 reference

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Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells

7 July 2018

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Diabetes and pancreatic cancer: chicken or egg?

7 July 2018

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Diabetes mellitus, fasting glucose, and risk of cause-specific death

7 July 2018

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The complexities of obesity and diabetes with the development and progression of pancreatic cancer

7 July 2018

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7 July 2018

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Metformin prevents tobacco carcinogen--induced lung tumorigenesis

7 July 2018

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Diabetes mellitus in pancreatic cancer and the need for diagnosis of asymptomatic disease

7 July 2018

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New strategies in pancreatic cancer: emerging epidemiologic and therapeutic concepts

7 July 2018

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AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation

7 July 2018

1 reference

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Metformin: a therapeutic opportunity in breast cancer

7 July 2018

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Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

7 July 2018

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The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

7 July 2018

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The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

7 July 2018

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7 July 2018

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Antidiabetic therapies affect risk of pancreatic cancer

7 July 2018

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New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer

7 July 2018

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Insulin and insulin-like growth factor signalling in neoplasia

7 July 2018

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

7 July 2018

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Body mass index and pancreatic cancer risk: A meta-analysis of prospective studies.

7 July 2018

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Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

7 July 2018

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

7 July 2018

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Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies

7 July 2018

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Restoration of Silenced Peutz-Jeghers Syndrome Gene, LKB1, Induces Apoptosis in Pancreatic Carcinoma Cells

7 July 2018

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

7 July 2018

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

7 July 2018

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Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis

7 July 2018

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Prediagnostic plasma C-peptide and pancreatic cancer risk in men and women.

7 July 2018

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Prospective study of hyperglycemia and cancer risk.

21 January 2018

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Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

21 January 2018

1 reference

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Prevention of pancreatic cancer induction in hamsters by metformin

21 January 2018

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Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.

21 January 2018

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Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

21 January 2018

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United Kingdom Prospective Diabetes Study (UKPDS). 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23663483

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23663483

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-13-235

1 reference

Dimensions Publication ID

4 August 2017

1012140741

0 references

Fatcat ID

release_pj3taukasrg6zejuysixddsx3a

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pj3taukasrg6zejuysixddsx3a

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3661399

1 reference

4 August 2017

1 reference