SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization (Q34729713)

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25 January 2020

title

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization (English)

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3

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Paula I. Moreira

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Sandra M. Cardoso

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Clary B Clish

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Pier Paolo Pandolfi

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1

Lydia W S Finley

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Arkaitz Carracedo

2

object named as

Arkaitz Carracedo

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5

Ainara Egia

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Marcia C Haigis

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author name string

Amanda Souza

4

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25 January 2020

Jiangwen Zhang

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Julie Teruya-Feldstein

7

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publication date

1 March 2011

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25 January 2020

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volume

19

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page(s)

416-428

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issue

3

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

25 January 2020

cites work

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Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

7 July 2018

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Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction

7 July 2018

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Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

7 July 2018

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

7 July 2018

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Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis

7 July 2018

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Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest

7 July 2018

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Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha

7 July 2018

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7 July 2018

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

7 July 2018

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The landscape of somatic copy-number alteration across human cancers

7 July 2018

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7 July 2018

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SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

7 July 2018

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Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria

7 July 2018

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HIF-1: upstream and downstream of cancer metabolism

7 July 2018

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Mitochondrial reactive oxygen species regulate hypoxic signaling

7 July 2018

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Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

7 July 2018

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Recent progress in the biology and physiology of sirtuins

7 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

7 July 2018

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Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

7 July 2018

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The molecular determinants of de novo nucleotide biosynthesis in cancer cells

7 July 2018

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Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover

7 July 2018

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A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

7 July 2018

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Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

7 July 2018

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

7 July 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

7 July 2018

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High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer

7 July 2018

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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

7 July 2018

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7 July 2018

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Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

7 July 2018

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7 July 2018

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The p53 tumor suppressor: critical regulator of life & death in cancer

7 July 2018

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Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

7 July 2018

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

7 July 2018

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7 July 2018

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Identification of ROS using oxidized DCFDA and flow-cytometry.

7 July 2018

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26 October 2018

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26 October 2018

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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Microsomal lipid peroxidation

26 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21397863

inferred from PubMed ID database lookup

12 December 2020

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Preparation, culture, and immortalization of mouse embryonic fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21397863

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2011.02.014

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25 January 2020

1 reference

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25 January 2020

1 reference