Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets (Q34750179)

4 August 2017

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title

Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets (English)

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4 August 2017

2

Adam Sapirstein

1 reference

4 August 2017

Tarek A Samad

1

1 reference

PubMed ID

12127725

4 August 2017

Clifford J Woolf

series ordinal

3

1 reference

4 August 2017

1 August 2002

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Trends in Molecular Medicine

4 August 2017

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4 August 2017

8

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4 August 2017

8

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4 August 2017

390-396

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Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Molecular basis of sickness behavior.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostaglandins and leukotrienes: advances in eicosanoid biology

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Cyclooxygenases: structural, cellular, and molecular biology

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostanoid receptors: structures, properties, and functions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Distribution and function of prostanoid receptors: studies from knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostanoid receptors: subtypes and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

The expanding superfamily of phospholipase A(2) enzymes: classification and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Mammalian secreted phospholipases A2 and their pathophysiological significance in inflammatory diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Calcium-independent phospholipase A(2): structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Function and inhibition of intracellular calcium-independent phospholipase A2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Structure and mechanism of human cytosolic phospholipase A(2).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

The role of calcium and phosphorylation of cytosolic phospholipase A2 in regulating arachidonic acid release in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Translocation of cytosolic phospholipase A2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Type II secretory phospholipase A2 associated with cell surfaces via C-terminal heparin-binding lysine residues augments stimulus-initiated delayed prostaglandin generation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Sensory neurons are PARtial to pain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

COX-2-Specific inhibitors--the emergence of a new class of analgesic and anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Regulated formation of eicosanoids

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Persistent accumulation of cyclooxygenase-1 (COX-1) expressing microglia/macrophages and upregulation by endothelium following spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Up-regulation of cyclooxygenase-1 and -2 in human gastric ulcer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Upregulation of cyclooxygenase-1 and the PGE2 receptor EP2 in rat and human mesangioproliferative glomerulonephritis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Mechanism of action of nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Spinal systems and pain processing: development of novel analgesic drugs with mechanistically defined models

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Immunology. Telling the brain about pain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Common structural features of MAPEG -- a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Cloning and expression of cDNA for a human thromboxane A2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Genetic and pharmacological analysis of prostanoid receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Distribution of the messenger RNA for the prostaglandin E receptor subtype EP3 in the mouse nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Prostaglandin and PPAR control of immune cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

A tetrodotoxin-resistant sodium current mediates inflammatory pain in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Effects of Prostaglandin E2 and Capsaicin on Behavior and Cerebrospinal Fluid Amino Acid Concentrations of Unanesthetized Rats: A Microdialysis Study

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Direct activation of rat spinal dorsal horn neurons by prostaglandin E2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Efficacy of cyclooxygenase-2-specific inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Nonsteroidal anti-inflammatory drugs, acetaminophen, cyclooxygenase 2, and fever.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

Mechanism of action of acetaminophen: is there a cyclooxygenase 3?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902383-3

7 January 2021

10.1016/S1471-4914(02)02383-3

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12127725