Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers (Q34751856)

4 August 2017

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title

Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers (English)

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4 August 2017

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David J Hughes

1

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4 August 2017

publication date

19 February 2008

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4 August 2017

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4 August 2017

volume

7

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4 August 2017

issue

3

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4 August 2017

page(s)

233-244

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https://scigraph.springernature.com/pub.10.1007/s10689-008-9181-0

4 August 2017

exact match

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cites work

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Methyl group metabolism gene polymorphisms as modifier of breast cancer risk in Italian BRCA1/2 carriers

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Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

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The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function

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Cancer susceptibility and the functions of BRCA1 and BRCA2

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A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes

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A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers

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Variation in cancer risks, by mutation position, in BRCA2 mutation carriers

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Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population

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CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers

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Emerging functions of BRCA2 in DNA recombination

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The genetics and genomics of cancer

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Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations.

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The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers

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Cancer risks in BRCA2 mutation carriers

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Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers

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AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study

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Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families

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Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers

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Evidence of haplotype insufficiency in human cells containing a germline mutation in BRCA1 or BRCA2.

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RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

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Relationship between estrogen levels, use of hormone replacement therapy, and breast cancer

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Polyglutamine repeat length in theAIB1 gene modifies breast cancer susceptibility inBRCA1 carriers

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A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

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A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joining.

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Variation in BRCA1 cancer risks by mutation position

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Breast cancer risk inBRCA1 andBRCA2 mutation carriers and polyglutamine repeat length in theAIB1 gene

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Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history.

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Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study

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Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS)

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A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

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Risk modifiers in carriers of brca1 mutations

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

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Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers.

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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Heritability of mammographic density, a risk factor for breast cancer.

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Association of BRCA2 polymorphism at codon 784 (Met/Val) with breast cancer risk and prognosis

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CGH-targeted linkage analysis reveals a possible BRCA1 modifier locus on chromosome 5q

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Variants in DNA double-strand break repair genes and breast cancer susceptibility

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The BRCA2 372 HH genotype is associated with risk of breast cancer in Australian women under age 60 years.

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Modifiers of risk of hereditary breast and ovarian cancer

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In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity

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Identification of the breast cancer susceptibility gene BRCA2

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Germline BRCA1 alterations in a population-based series of ovarian cancer cases

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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

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Biallelic inactivation of BRCA2 in Fanconi anemia

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Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families

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12 December 2020

A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers

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12 December 2020

Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study

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Polyglutamine repeat length in the NCOA3 does not affect risk in familial breast cancer

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12 December 2020

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 germ-line mutations

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12 December 2020

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

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12 December 2020

Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2

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Inherited predisposition and breast cancer: modifiers of BRCA1/2-associated breast cancer risk

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BRCA2 arg372hispolymorphism and epithelial ovarian cancer risk

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12 December 2020

Ovarian cancer, oral contraceptives, and BRCA mutations

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12 December 2020

The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

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12 December 2020

"Other" breast cancer susceptibility genes: searching for more holy grail

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12 December 2020

Lessons learned from BRCA1 and BRCA2.

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12 December 2020

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations

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12 December 2020

Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of the BRCA2 gene?

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12 December 2020

Polymorphic repeat in AIB1 does not alter breast cancer risk

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12 December 2020

Androgen receptor CAG repeat length in Jewish Israeli women who are BRCA1/2 mutation carriers: association with breast/ovarian cancer phenotype

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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

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12 December 2020

Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes

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Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2

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A common coding variant in CASP8 is associated with breast cancer risk

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Epidemiology of breast cancer among BRCA mutation carriers: an overview

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The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk in Polish BRCA1 mutation carriers

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A haplotype containing thep53polymorphisms Ins16bp and Arg72Pro modifies cancer risk inBRCA2mutation carriers

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12 December 2020

A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers

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12 December 2020

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2

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12 December 2020

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

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12 December 2020

Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women.

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12 December 2020

Prevalence of BRCA1 mutation carriers among U.S. non-Hispanic Whites.

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12 December 2020

Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group.

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12 December 2020

Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour

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12 December 2020

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition

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12 December 2020

Comparison of BRCA1 polymorphisms, rare sequence variants and/or missense mutations in unaffected and breast/ovarian cancer populations

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12 December 2020

Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.

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12 December 2020

Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat

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12 December 2020

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

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12 December 2020

Breast cancer risk reduction associated with the RAD51 polymorphism among carriers of the BRCA1 5382insC mutation in Poland

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12 December 2020

Efficient selective screening of haplotype tag SNPs

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12 December 2020

Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation

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12 December 2020

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

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12 December 2020

Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium

1 reference

12 December 2020

10.1007/S10689-008-9181-0

Identifiers

DOI

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Dimensions Publication ID

4 August 2017

1015516262

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Fatcat ID

release_3mkaqm3z3rgt3i2ciophxinupq

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Fatcat

https://api.fatcat.wiki/v0/release/3mkaqm3z3rgt3i2ciophxinupq

24 November 2022

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