Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle (Q34768447)

4 August 2017

Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle (English)

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4 August 2017

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P Lau

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4 August 2017

R L Fitzsimmons

2

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4 August 2017

M A Pearen

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4 August 2017

M J Watt

4

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4 August 2017

G E O Muscat

5

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4 August 2017

language of work or name

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29 January 2011

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4 August 2017

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4 August 2017

54

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4 August 2017

5

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4 August 2017

1169-1180

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2046-3

4 August 2017

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cites work

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle.

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TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.

7 July 2018

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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.

7 July 2018

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Targeting SGK1 in diabetes

7 July 2018

1 reference

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Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation

7 July 2018

1 reference

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NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse

7 July 2018

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7 July 2018

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Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

7 July 2018

1 reference

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Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.

7 July 2018

1 reference

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Bifunctional role of Rev-erbalpha in adipocyte differentiation

7 July 2018

1 reference

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Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

7 July 2018

1 reference

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7 July 2018

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OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

7 July 2018

1 reference

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Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line

7 July 2018

1 reference

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Orphan nuclear receptors: therapeutic opportunities in skeletal muscle.

7 July 2018

1 reference

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ROR alpha in genetic control of cerebellum development: 50 staggering years

7 July 2018

1 reference

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Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease

7 July 2018

1 reference

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RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR

7 July 2018

1 reference

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The "CholesteROR" protective pathway in the vascular system

7 July 2018

1 reference

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Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression

7 July 2018

1 reference

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

7 July 2018

1 reference

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Regulation of cholesterol homeostasis and lipid metabolism in skeletal muscle by liver X receptors.

7 July 2018

1 reference

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Identification of Reverb(alpha) as a novel ROR(alpha) target gene

7 July 2018

1 reference

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

Pathophysiology and pharmacological treatment of insulin resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply

7 July 2018

1 reference

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Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071927

The structural integrity of ROR alpha isoforms is mutated in staggerer mice: cerebellar coexpression of ROR alpha1 and ROR alpha4.

7 July 2018

1 reference

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Disruption of the nuclear hormone receptor RORalpha in staggerer mice

7 July 2018

1 reference

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The nonconserved hinge region and distinct amino-terminal domains of the ROR alpha orphan nuclear receptor isoforms are required for proper DNA bending and ROR alpha-DNA interactions

7 July 2018

1 reference

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Effects of cold acclimation on the energetic metabolism of the staggerer mutant mouse

7 July 2018

1 reference

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The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

7 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Evaluating the glucose tolerance test in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Association of SGK 1 Gene polymorphisms with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Inhibition of adipocyte differentiation by RORalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2046-3

Severe atherosclerosis and hypoalphalipoproteinemia in the staggerer mouse, a mutant of the nuclear receptor RORalpha

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21279323

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21279323

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00125-011-2046-3

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference